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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD1
All Species:
25.45
Human Site:
Y385
Identified Species:
62.22
UniProt:
Q8NB12
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NB12
NP_938015.1
490
56617
Y385
V
D
G
Y
M
K
L
Y
H
P
N
N
A
Q
L
Chimpanzee
Pan troglodytes
XP_514316
454
52196
S340
A
M
C
Q
A
I
I
S
S
N
S
E
R
L
P
Rhesus Macaque
Macaca mulatta
XP_001093225
479
54825
Y374
L
C
S
H
R
K
L
Y
H
P
N
N
A
Q
L
Dog
Lupus familis
XP_852104
490
56440
Y385
V
D
G
Y
M
K
L
Y
H
P
N
N
A
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
P97443
485
55988
Y380
V
D
G
Y
M
K
L
Y
H
H
N
N
A
Q
L
Rat
Rattus norvegicus
Q7M6Z3
433
49630
Y338
V
F
E
D
S
N
V
Y
M
L
H
M
M
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510487
490
56179
Y385
V
D
G
Y
M
K
L
Y
H
P
N
N
A
Q
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085463
478
54748
Y368
I
D
G
Y
M
K
I
Y
H
P
N
N
A
Q
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09415
429
48527
P333
D
H
N
V
H
R
I
P
V
L
R
C
L
Y
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7XJS0
480
54809
Y367
E
K
L
Q
V
K
L
Y
H
S
F
S
I
P
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.7
85.5
96.1
N.A.
93.6
28.5
N.A.
87.5
N.A.
73.4
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
100
46.1
90.1
99.1
N.A.
97.7
49.5
N.A.
95.5
N.A.
84.9
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
100
0
66.6
100
N.A.
93.3
13.3
N.A.
100
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
13.3
80
100
N.A.
93.3
26.6
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
0
0
0
60
0
0
% A
% Cys:
0
10
10
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
50
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
10
10
0
0
0
70
10
10
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
30
0
0
0
0
0
10
0
10
% I
% Lys:
0
10
0
0
0
70
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
10
0
0
0
60
0
0
20
0
0
10
10
70
% L
% Met:
0
10
0
0
50
0
0
0
10
0
0
10
10
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
10
60
60
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
50
0
0
0
10
10
% P
% Gln:
0
0
0
20
0
0
0
0
0
0
0
0
0
60
10
% Q
% Arg:
0
0
0
0
10
10
0
0
0
0
10
0
10
0
0
% R
% Ser:
0
0
10
0
10
0
0
10
10
10
10
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
50
0
0
10
10
0
10
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
50
0
0
0
80
0
0
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _