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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM184A
All Species:
16.06
Human Site:
S280
Identified Species:
29.44
UniProt:
Q8NB25
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NB25
NP_001093881.1
1140
132965
S280
T
A
E
S
L
Q
A
S
K
E
K
E
A
D
L
Chimpanzee
Pan troglodytes
XP_001163920
1138
132636
S278
T
A
E
S
L
Q
A
S
K
E
K
E
A
D
L
Rhesus Macaque
Macaca mulatta
XP_001110223
1143
133027
S283
T
A
E
S
L
Q
A
S
K
E
K
E
A
D
L
Dog
Lupus familis
XP_533480
1140
132525
S280
T
A
E
S
L
Q
A
S
K
E
K
E
A
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q0KK56
942
107582
Q199
S
Q
R
P
E
M
H
Q
V
L
L
E
V
E
R
Rat
Rattus norvegicus
Q9JLT0
1976
228947
R567
H
S
K
F
Q
K
P
R
Q
L
K
D
K
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521819
525
61386
Chicken
Gallus gallus
P10587
1979
228777
E703
L
D
A
H
L
V
L
E
Q
L
R
C
N
G
V
Frog
Xenopus laevis
NP_001087755
1113
130052
C254
T
A
E
S
L
H
T
C
K
Q
K
E
A
E
L
Zebra Danio
Brachydanio rerio
XP_683302
1145
133823
W287
T
A
E
N
L
L
A
W
K
K
T
E
A
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q99323
2057
236625
L938
V
T
K
Q
E
E
K
L
V
Q
K
E
D
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11102
1130
131467
H297
E
L
E
A
L
R
D
H
E
E
A
L
K
E
E
Sea Urchin
Strong. purpuratus
XP_795044
1073
122967
S263
K
A
E
A
A
L
D
S
R
E
G
D
A
H
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.9
94.2
N.A.
26.3
20.8
N.A.
38.1
20.9
66
58.4
N.A.
20.4
N.A.
21.9
32.8
Protein Similarity:
100
99.3
99.1
97.1
N.A.
46.1
36.8
N.A.
42.2
36.9
83.3
78.4
N.A.
34.6
N.A.
44.8
54.5
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
0
6.6
66.6
60
N.A.
20
N.A.
20
33.3
P-Site Similarity:
100
100
100
100
N.A.
20
40
N.A.
0
26.6
80
80
N.A.
46.6
N.A.
46.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
8
16
8
0
39
0
0
0
8
0
54
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
0
0
0
16
0
0
0
0
16
8
31
8
% D
% Glu:
8
0
62
0
16
8
0
8
8
47
0
62
0
39
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% G
% His:
8
0
0
8
0
8
8
8
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
16
0
0
8
8
0
47
8
54
0
16
0
0
% K
% Leu:
8
8
0
0
62
16
8
8
0
24
8
8
0
0
54
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
8
31
0
8
16
16
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
8
0
8
8
0
8
0
0
0
8
% R
% Ser:
8
8
0
39
0
0
0
39
0
0
0
0
0
0
0
% S
% Thr:
47
8
0
0
0
0
8
0
0
0
8
0
0
0
0
% T
% Val:
8
0
0
0
0
8
0
0
16
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _