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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYT14
All Species:
15.45
Human Site:
S400
Identified Species:
30.91
UniProt:
Q8NB59
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NB59
NP_001139734.1
555
62287
S400
Q
M
S
V
S
E
M
S
C
S
E
S
T
S
S
Chimpanzee
Pan troglodytes
XP_514169
555
62241
S400
Q
M
S
V
S
E
M
S
C
S
E
S
T
S
S
Rhesus Macaque
Macaca mulatta
XP_001108818
586
65494
I431
E
H
G
S
V
P
E
I
L
I
G
L
L
Y
N
Dog
Lupus familis
XP_852193
524
58237
K370
K
E
K
I
V
G
E
K
I
F
Y
L
T
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7TN84
555
62025
S400
Q
V
S
L
S
E
A
S
C
G
D
S
T
S
S
Rat
Rattus norvegicus
O08625
523
58992
F369
I
D
L
G
E
I
M
F
S
L
C
Y
L
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509192
645
72314
I490
S
Q
M
S
M
S
E
I
S
C
E
S
T
S
S
Chicken
Gallus gallus
P47191
424
47487
K270
R
D
L
Q
S
A
E
K
E
E
Q
E
K
L
G
Frog
Xenopus laevis
NP_001087543
546
60949
C392
M
S
M
S
E
M
S
C
T
E
S
T
S
S
C
Zebra Danio
Brachydanio rerio
XP_693124
579
63796
S424
Q
A
S
M
S
D
V
S
C
S
E
T
A
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34693
441
49885
K287
I
A
P
P
P
D
D
K
E
A
E
K
S
L
G
Sea Urchin
Strong. purpuratus
XP_001177199
422
46964
S267
Y
S
S
T
S
D
L
S
D
S
N
S
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
94
82.5
N.A.
93.8
21.7
N.A.
81.2
21.7
81.9
69.4
N.A.
N.A.
N.A.
21
37.4
Protein Similarity:
100
100
94.5
85.7
N.A.
97.4
39.6
N.A.
83.2
38
89.5
80.6
N.A.
N.A.
N.A.
39.4
53.6
P-Site Identity:
100
100
0
6.6
N.A.
66.6
6.6
N.A.
33.3
6.6
6.6
60
N.A.
N.A.
N.A.
6.6
46.6
P-Site Similarity:
100
100
13.3
20
N.A.
86.6
13.3
N.A.
33.3
20
20
86.6
N.A.
N.A.
N.A.
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
0
9
9
0
0
9
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
34
9
9
0
0
0
9
% C
% Asp:
0
17
0
0
0
25
9
0
9
0
9
0
0
0
0
% D
% Glu:
9
9
0
0
17
25
34
0
17
17
42
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% F
% Gly:
0
0
9
9
0
9
0
0
0
9
9
0
0
0
17
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
9
0
9
0
17
9
9
0
0
0
0
0
% I
% Lys:
9
0
9
0
0
0
0
25
0
0
0
9
9
9
0
% K
% Leu:
0
0
17
9
0
0
9
0
9
9
0
17
17
17
9
% L
% Met:
9
17
17
9
9
9
25
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% N
% Pro:
0
0
9
9
9
9
0
0
0
0
0
0
0
9
0
% P
% Gln:
34
9
0
9
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
17
42
25
50
9
9
42
17
34
9
42
25
59
50
% S
% Thr:
0
0
0
9
0
0
0
0
9
0
0
17
42
0
9
% T
% Val:
0
9
0
17
17
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
9
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _