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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UNC13C All Species: 22.73
Human Site: S997 Identified Species: 55.56
UniProt: Q8NB66 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NB66 NP_001074003.1 2214 250911 S997 K I L A G D S S S V D E K A R
Chimpanzee Pan troglodytes XP_510424 2217 251206 S1000 K I L A G D S S S V D E K A R
Rhesus Macaque Macaca mulatta XP_001088968 2218 251439 S999 R I L A G D S S S V D E K A R
Dog Lupus familis XP_544689 2217 251282 S1000 K I L A G D S S S V D E K A R
Cat Felis silvestris
Mouse Mus musculus Q8K0T7 2210 249825 S993 K I L A G D S S S M D E K A R
Rat Rattus norvegicus Q62770 2204 249117 S987 K I L A G D S S S V D E K A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_413798 2097 238862 L970 I H V F K K T L Q A L I Y P I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038630 1742 197943 E628 P T Y C Y E C E G L L W G I A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726615 3183 360057 K1934 K N N Q D K I K E D E M I K D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P27715 2155 245213 N972 I D A A P N M N V A R T K T S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.1 94.5 N.A. 91 90.6 N.A. N.A. 77.6 N.A. 49.8 N.A. 36.1 N.A. 37.4 N.A.
Protein Similarity: 100 99.5 98.2 96.9 N.A. 94.4 94.1 N.A. N.A. 85.9 N.A. 62 N.A. 50.4 N.A. 55 N.A.
P-Site Identity: 100 100 93.3 100 N.A. 93.3 100 N.A. N.A. 0 N.A. 0 N.A. 6.6 N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 13.3 N.A. 13.3 N.A. 13.3 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 70 0 0 0 0 0 20 0 0 0 60 10 % A
% Cys: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 60 0 0 0 10 60 0 0 0 10 % D
% Glu: 0 0 0 0 0 10 0 10 10 0 10 60 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 60 0 0 0 10 0 0 0 10 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 20 60 0 0 0 0 10 0 0 0 0 10 10 10 10 % I
% Lys: 60 0 0 0 10 20 0 10 0 0 0 0 70 10 0 % K
% Leu: 0 0 60 0 0 0 0 10 0 10 20 0 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 10 0 10 0 0 0 % M
% Asn: 0 10 10 0 0 10 0 10 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 60 % R
% Ser: 0 0 0 0 0 0 60 60 60 0 0 0 0 0 10 % S
% Thr: 0 10 0 0 0 0 10 0 0 0 0 10 0 10 0 % T
% Val: 0 0 10 0 0 0 0 0 10 50 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 10 0 10 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _