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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC13C
All Species:
3.33
Human Site:
T622
Identified Species:
8.15
UniProt:
Q8NB66
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NB66
NP_001074003.1
2214
250911
T622
G
Q
T
E
T
E
N
T
E
T
V
D
S
G
M
Chimpanzee
Pan troglodytes
XP_510424
2217
251206
V625
E
I
E
N
T
E
T
V
D
S
G
M
S
N
G
Rhesus Macaque
Macaca mulatta
XP_001088968
2218
251439
V624
E
I
E
N
T
E
T
V
D
S
G
M
S
N
G
Dog
Lupus familis
XP_544689
2217
251282
V625
E
I
E
N
T
E
T
V
E
S
G
M
S
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0T7
2210
249825
D618
I
E
N
T
E
T
V
D
S
G
M
S
N
S
M
Rat
Rattus norvegicus
Q62770
2204
249117
T612
G
E
I
E
N
T
E
T
V
D
S
G
M
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413798
2097
238862
Q604
S
Q
E
Q
N
V
A
Q
D
A
Q
Q
Y
P
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038630
1742
197943
Y262
S
P
T
G
S
S
R
Y
A
S
S
G
E
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726615
3183
360057
Y1385
D
E
Q
E
D
F
N
Y
K
N
R
C
D
S
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P27715
2155
245213
I606
R
V
C
A
D
L
G
I
K
S
S
Q
A
S
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.1
94.5
N.A.
91
90.6
N.A.
N.A.
77.6
N.A.
49.8
N.A.
36.1
N.A.
37.4
N.A.
Protein Similarity:
100
99.5
98.2
96.9
N.A.
94.4
94.1
N.A.
N.A.
85.9
N.A.
62
N.A.
50.4
N.A.
55
N.A.
P-Site Identity:
100
20
20
26.6
N.A.
6.6
20
N.A.
N.A.
6.6
N.A.
6.6
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
33.3
33.3
33.3
N.A.
26.6
26.6
N.A.
N.A.
20
N.A.
20
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
0
10
10
0
0
10
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
0
0
0
20
0
0
10
30
10
0
10
10
0
0
% D
% Glu:
30
30
40
30
10
40
10
0
20
0
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
0
0
10
0
0
10
0
0
10
30
20
0
10
30
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
30
10
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
30
10
0
20
% M
% Asn:
0
0
10
30
20
0
20
0
0
10
0
0
10
30
10
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
20
10
10
0
0
0
10
0
0
10
20
0
0
0
% Q
% Arg:
10
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% R
% Ser:
20
0
0
0
10
10
0
0
10
50
30
10
40
40
10
% S
% Thr:
0
0
20
10
40
20
30
20
0
10
0
0
0
0
0
% T
% Val:
0
10
0
0
0
10
10
30
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
20
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _