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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KDM1B All Species: 13.03
Human Site: S186 Identified Species: 31.85
UniProt: Q8NB78 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NB78 NP_694587.3 823 92226 S186 P E T S D H C S L P E D L R V
Chimpanzee Pan troglodytes XP_518258 923 103081 S286 P E T S D H C S L P E D L R V
Rhesus Macaque Macaca mulatta XP_001097626 619 68608 T34 M S P S C T S T N R A A A T G
Dog Lupus familis XP_535900 558 62499
Cat Felis silvestris
Mouse Mus musculus Q8CIG3 826 92614 S186 P D T P D H C S F P E D L R V
Rat Rattus norvegicus NP_001100813 824 92537 S186 P D T P D H C S F P E D L R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418920 896 99632 H262 V T Q K T F A H M E T S N K V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW97 890 98370 I190 P D I S R S G I L G H R V F L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21988 824 93415 L193 N E F G H P P L L Q N N I S Y
Sea Urchin Strong. purpuratus XP_782860 837 93222 V227 T P S D H C T V L Q D H R V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89 74.4 65.3 N.A. 89.7 89.8 N.A. N.A. 78.4 N.A. N.A. N.A. 20.7 N.A. 35.1 50
Protein Similarity: 100 89 74.8 66.7 N.A. 94.3 94.9 N.A. N.A. 84.2 N.A. N.A. N.A. 39.7 N.A. 53.8 69.4
P-Site Identity: 100 100 6.6 0 N.A. 80 80 N.A. N.A. 6.6 N.A. N.A. N.A. 20 N.A. 13.3 6.6
P-Site Similarity: 100 100 13.3 0 N.A. 86.6 86.6 N.A. N.A. 20 N.A. N.A. N.A. 40 N.A. 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 10 10 10 0 0 % A
% Cys: 0 0 0 0 10 10 40 0 0 0 0 0 0 0 0 % C
% Asp: 0 30 0 10 40 0 0 0 0 0 10 40 0 0 0 % D
% Glu: 0 30 0 0 0 0 0 0 0 10 40 0 0 0 10 % E
% Phe: 0 0 10 0 0 10 0 0 20 0 0 0 0 10 0 % F
% Gly: 0 0 0 10 0 0 10 0 0 10 0 0 0 0 10 % G
% His: 0 0 0 0 20 40 0 10 0 0 10 10 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 10 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 0 0 0 0 10 50 0 0 0 40 0 10 % L
% Met: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 10 0 10 10 10 0 0 % N
% Pro: 50 10 10 20 0 10 10 0 0 40 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 20 0 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 10 0 10 10 40 0 % R
% Ser: 0 10 10 40 0 10 10 40 0 0 0 10 0 10 0 % S
% Thr: 10 10 40 0 10 10 10 10 0 0 10 0 0 10 0 % T
% Val: 10 0 0 0 0 0 0 10 0 0 0 0 10 10 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _