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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM1B
All Species:
11.21
Human Site:
T751
Identified Species:
27.41
UniProt:
Q8NB78
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NB78
NP_694587.3
823
92226
T751
E
Q
E
V
P
D
P
T
K
Y
F
V
T
R
W
Chimpanzee
Pan troglodytes
XP_518258
923
103081
I851
E
Q
E
V
P
D
P
I
K
Y
F
V
T
R
W
Rhesus Macaque
Macaca mulatta
XP_001097626
619
68608
K548
Q
E
V
P
D
P
T
K
Y
F
V
T
R
W
S
Dog
Lupus familis
XP_535900
558
62499
K487
Q
E
V
P
D
P
T
K
Y
F
V
T
R
W
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIG3
826
92614
T754
E
Q
E
I
P
E
P
T
K
Y
F
V
T
R
W
Rat
Rattus norvegicus
NP_001100813
824
92537
T752
E
Q
E
I
P
D
P
T
K
Y
F
V
T
R
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418920
896
99632
V824
E
Q
E
V
P
D
P
V
K
F
F
V
T
R
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW97
890
98370
K745
N
T
S
V
P
Q
P
K
E
T
V
V
T
R
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21988
824
93415
G743
S
A
V
I
N
P
L
G
H
M
M
S
H
W
G
Sea Urchin
Strong. purpuratus
XP_782860
837
93222
T763
V
Q
K
L
K
E
M
T
E
K
E
V
M
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89
74.4
65.3
N.A.
89.7
89.8
N.A.
N.A.
78.4
N.A.
N.A.
N.A.
20.7
N.A.
35.1
50
Protein Similarity:
100
89
74.8
66.7
N.A.
94.3
94.9
N.A.
N.A.
84.2
N.A.
N.A.
N.A.
39.7
N.A.
53.8
69.4
P-Site Identity:
100
93.3
0
0
N.A.
86.6
93.3
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
46.6
N.A.
0
20
P-Site Similarity:
100
93.3
20
20
N.A.
100
100
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
53.3
N.A.
6.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
20
40
0
0
0
0
0
0
0
0
0
% D
% Glu:
50
20
50
0
0
20
0
0
20
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
30
50
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% H
% Ile:
0
0
0
30
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
10
0
0
30
50
10
0
0
0
0
10
% K
% Leu:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
10
10
0
10
0
0
% M
% Asn:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
20
60
30
60
0
0
0
0
0
0
0
0
% P
% Gln:
20
60
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
20
60
0
% R
% Ser:
10
0
10
0
0
0
0
0
0
0
0
10
0
0
20
% S
% Thr:
0
10
0
0
0
0
20
40
0
10
0
20
60
0
0
% T
% Val:
10
0
30
40
0
0
0
10
0
0
30
70
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
60
% W
% Tyr:
0
0
0
0
0
0
0
0
20
40
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _