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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FANCB All Species: 7.58
Human Site: S531 Identified Species: 27.78
UniProt: Q8NB91 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NB91 NP_001018123.1 859 97726 S531 Q N R V I K L S T N P F P A P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001099768 860 97761 S532 Q N R V I K L S T N P F P A P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q5XJY6 703 80070 Q399 F I F L N K I Q Q H I S F K D
Rat Rattus norvegicus XP_576954 853 97171 S528 Q S Q L I S L S M N S F P E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515454 875 98684 K543 Q N K V I K L K T E S F S A T
Chicken Gallus gallus XP_416827 969 107492 N631 R N K I I K L N K V F S A L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001035726 807 90769 G503 S E F E S C L G P S A V K R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.8 N.A. N.A. 39.7 50.1 N.A. 51.2 38.7 N.A. 24.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 97.3 N.A. N.A. 57.5 68.6 N.A. 68.2 57.2 N.A. 49 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 N.A. N.A. 6.6 46.6 N.A. 60 26.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 N.A. N.A. 26.6 66.6 N.A. 66.6 53.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 15 0 15 43 0 % A
% Cys: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % D
% Glu: 0 15 0 15 0 0 0 0 0 15 0 0 0 15 0 % E
% Phe: 15 0 29 0 0 0 0 0 0 0 15 58 15 0 0 % F
% Gly: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % H
% Ile: 0 15 0 15 72 0 15 0 0 0 15 0 0 0 15 % I
% Lys: 0 0 29 0 0 72 0 15 15 0 0 0 15 15 0 % K
% Leu: 0 0 0 29 0 0 86 0 0 0 0 0 0 15 0 % L
% Met: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % M
% Asn: 0 58 0 0 15 0 0 15 0 43 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 15 0 29 0 43 0 29 % P
% Gln: 58 0 15 0 0 0 0 15 15 0 0 0 0 0 0 % Q
% Arg: 15 0 29 0 0 0 0 0 0 0 0 0 0 15 0 % R
% Ser: 15 15 0 0 15 15 0 43 0 15 29 29 15 0 15 % S
% Thr: 0 0 0 0 0 0 0 0 43 0 0 0 0 0 29 % T
% Val: 0 0 0 43 0 0 0 0 0 15 0 15 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _