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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DTWD2 All Species: 16.67
Human Site: S205 Identified Species: 45.83
UniProt: Q8NBA8 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBA8 NP_775937.1 298 33416 S205 K Q V Q L K T S I S S Q Y V I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086999 298 33530 S205 K Q V Q L K T S I S S Q Y V I
Dog Lupus familis XP_850228 319 36314 S226 K Q V Q L K T S I S S Q Y V I
Cat Felis silvestris
Mouse Mus musculus Q9D0U1 298 33084 S205 K Q V Q L K T S V C S Q Y V I
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512672 270 30276 Y182 K T S I S S Q Y V I R T Q P T
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649713 251 28172 I164 A V G I S D Y I I R T Q P T E
Honey Bee Apis mellifera XP_394689 252 28141 S165 K L V G V P T S E Y V I R T Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793124 247 27693 G160 Q V Q F T N S G S S E Y T I R
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001146773 262 28319 S175 D S R A D G D S M F E S D L V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.6 72.7 N.A. 84.5 N.A. N.A. 73.4 N.A. N.A. N.A. N.A. 36.5 32.8 N.A. 37.2
Protein Similarity: 100 N.A. 97.6 77.7 N.A. 88.9 N.A. N.A. 79.8 N.A. N.A. N.A. N.A. 50.3 50 N.A. 54
P-Site Identity: 100 N.A. 100 100 N.A. 86.6 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. 13.3 26.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. 20 33.3 N.A. 26.6
Percent
Protein Identity: N.A. 29.8 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 45.9 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % C
% Asp: 12 0 0 0 12 12 12 0 0 0 0 0 12 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 12 0 23 0 0 0 12 % E
% Phe: 0 0 0 12 0 0 0 0 0 12 0 0 0 0 0 % F
% Gly: 0 0 12 12 0 12 0 12 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 23 0 0 0 12 45 12 0 12 0 12 45 % I
% Lys: 67 0 0 0 0 45 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 12 0 0 45 0 0 0 0 0 0 0 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 12 0 0 0 0 0 0 12 12 0 % P
% Gln: 12 45 12 45 0 0 12 0 0 0 0 56 12 0 12 % Q
% Arg: 0 0 12 0 0 0 0 0 0 12 12 0 12 0 12 % R
% Ser: 0 12 12 0 23 12 12 67 12 45 45 12 0 0 0 % S
% Thr: 0 12 0 0 12 0 56 0 0 0 12 12 12 23 12 % T
% Val: 0 23 56 0 12 0 0 0 23 0 12 0 0 45 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 12 12 0 12 0 12 45 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _