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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTWD2
All Species:
13.94
Human Site:
S208
Identified Species:
38.33
UniProt:
Q8NBA8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBA8
NP_775937.1
298
33416
S208
Q
L
K
T
S
I
S
S
Q
Y
V
I
R
M
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086999
298
33530
S208
Q
L
K
T
S
I
S
S
Q
Y
V
I
R
M
Q
Dog
Lupus familis
XP_850228
319
36314
S229
Q
L
K
T
S
I
S
S
Q
Y
V
I
R
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0U1
298
33084
S208
Q
L
K
T
S
V
C
S
Q
Y
V
I
R
M
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512672
270
30276
R185
I
S
S
Q
Y
V
I
R
T
Q
P
T
N
R
C
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649713
251
28172
T167
I
S
D
Y
I
I
R
T
Q
P
T
E
G
C
L
Honey Bee
Apis mellifera
XP_394689
252
28141
V168
G
V
P
T
S
E
Y
V
I
R
T
Q
P
T
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793124
247
27693
E163
F
T
N
S
G
S
S
E
Y
T
I
R
T
Q
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146773
262
28319
E178
A
D
G
D
S
M
F
E
S
D
L
V
V
R
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
72.7
N.A.
84.5
N.A.
N.A.
73.4
N.A.
N.A.
N.A.
N.A.
36.5
32.8
N.A.
37.2
Protein Similarity:
100
N.A.
97.6
77.7
N.A.
88.9
N.A.
N.A.
79.8
N.A.
N.A.
N.A.
N.A.
50.3
50
N.A.
54
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
20
26.6
N.A.
20
Percent
Protein Identity:
N.A.
29.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
45.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
0
12
12
% C
% Asp:
0
12
12
12
0
0
0
0
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
12
0
23
0
0
0
12
0
0
12
% E
% Phe:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
12
0
12
0
0
0
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
23
0
0
0
12
45
12
0
12
0
12
45
0
0
0
% I
% Lys:
0
0
45
0
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
0
45
0
0
0
0
0
0
0
0
12
0
0
0
12
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
34
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
12
12
0
12
0
12
% P
% Gln:
45
0
0
12
0
0
0
0
56
12
0
12
0
12
45
% Q
% Arg:
0
0
0
0
0
0
12
12
0
12
0
12
45
23
0
% R
% Ser:
0
23
12
12
67
12
45
45
12
0
0
0
0
0
0
% S
% Thr:
0
12
0
56
0
0
0
12
12
12
23
12
12
23
0
% T
% Val:
0
12
0
0
0
23
0
12
0
0
45
12
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
12
0
12
0
12
45
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _