KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTWD2
All Species:
3.64
Human Site:
S21
Identified Species:
10
UniProt:
Q8NBA8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBA8
NP_775937.1
298
33416
S21
V
A
R
P
S
G
A
S
S
S
Q
T
P
N
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086999
298
33530
S21
V
A
R
P
P
G
A
S
R
S
Q
T
P
N
A
Dog
Lupus familis
XP_850228
319
36314
V44
E
K
W
P
T
F
F
V
T
Y
G
V
I
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0U1
298
33084
L21
A
P
P
P
S
G
A
L
A
S
P
T
P
D
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512672
270
30276
E22
D
G
G
E
I
G
G
E
D
A
G
G
L
W
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649713
251
28172
Honey Bee
Apis mellifera
XP_394689
252
28141
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793124
247
27693
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146773
262
28319
G17
D
C
D
D
G
D
G
G
V
A
A
A
S
S
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
72.7
N.A.
84.5
N.A.
N.A.
73.4
N.A.
N.A.
N.A.
N.A.
36.5
32.8
N.A.
37.2
Protein Similarity:
100
N.A.
97.6
77.7
N.A.
88.9
N.A.
N.A.
79.8
N.A.
N.A.
N.A.
N.A.
50.3
50
N.A.
54
P-Site Identity:
100
N.A.
80
13.3
N.A.
46.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
0
N.A.
0
P-Site Similarity:
100
N.A.
80
26.6
N.A.
66.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
0
0
N.A.
0
Percent
Protein Identity:
N.A.
29.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
45.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
23
0
0
0
0
34
0
12
23
12
12
0
0
12
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
23
0
12
12
0
12
0
0
12
0
0
0
0
12
23
% D
% Glu:
12
0
0
12
0
0
0
12
0
0
0
0
0
0
23
% E
% Phe:
0
0
0
0
0
12
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
12
0
12
45
23
12
0
0
23
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% N
% Pro:
0
12
12
45
12
0
0
0
0
0
12
0
34
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% Q
% Arg:
0
0
23
0
0
0
0
0
12
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
23
0
0
23
12
34
0
0
12
12
12
% S
% Thr:
0
0
0
0
12
0
0
0
12
0
0
34
0
0
0
% T
% Val:
23
0
0
0
0
0
0
12
12
0
0
12
0
0
0
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _