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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DTWD2 All Species: 13.03
Human Site: Y189 Identified Species: 35.83
UniProt: Q8NBA8 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBA8 NP_775937.1 298 33416 Y189 S Q A K D I F Y K N S L F R H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086999 298 33530 Y189 S Q A K D I F Y K N S L F R H
Dog Lupus familis XP_850228 319 36314 Y210 S Q A K D I F Y K N S L F R L
Cat Felis silvestris
Mouse Mus musculus Q9D0U1 298 33084 Y189 S Q A K D I F Y K N S L F R L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512672 270 30276 F166 I F Y K N S L F R L P K Q V Q
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649713 251 28172 H148 Y A S S P A L H R L R Q V K L
Honey Bee Apis mellifera XP_394689 252 28141 P149 K A I Y H S S P T L C V L Q A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793124 247 27693 A144 Q A T S I F K A N A M F Q I P
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001146773 262 28319 G159 L A V L A S L G A V P V A L P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.6 72.7 N.A. 84.5 N.A. N.A. 73.4 N.A. N.A. N.A. N.A. 36.5 32.8 N.A. 37.2
Protein Similarity: 100 N.A. 97.6 77.7 N.A. 88.9 N.A. N.A. 79.8 N.A. N.A. N.A. N.A. 50.3 50 N.A. 54
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. 0 0 N.A. 0
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 N.A. N.A. 26.6 N.A. N.A. N.A. N.A. 26.6 13.3 N.A. 0
Percent
Protein Identity: N.A. 29.8 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 45.9 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 0 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 6.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 45 45 0 12 12 0 12 12 12 0 0 12 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % C
% Asp: 0 0 0 0 45 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 12 0 0 0 12 45 12 0 0 0 12 45 0 0 % F
% Gly: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 12 0 0 12 0 0 0 0 0 0 23 % H
% Ile: 12 0 12 0 12 45 0 0 0 0 0 0 0 12 0 % I
% Lys: 12 0 0 56 0 0 12 0 45 0 0 12 0 12 0 % K
% Leu: 12 0 0 12 0 0 34 0 0 34 0 45 12 12 34 % L
% Met: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % M
% Asn: 0 0 0 0 12 0 0 0 12 45 0 0 0 0 0 % N
% Pro: 0 0 0 0 12 0 0 12 0 0 23 0 0 0 23 % P
% Gln: 12 45 0 0 0 0 0 0 0 0 0 12 23 12 12 % Q
% Arg: 0 0 0 0 0 0 0 0 23 0 12 0 0 45 0 % R
% Ser: 45 0 12 23 0 34 12 0 0 0 45 0 0 0 0 % S
% Thr: 0 0 12 0 0 0 0 0 12 0 0 0 0 0 0 % T
% Val: 0 0 12 0 0 0 0 0 0 12 0 23 12 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 0 12 12 0 0 0 45 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _