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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NHLRC2
All Species:
28.18
Human Site:
S217
Identified Species:
62
UniProt:
Q8NBF2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBF2
NP_940916.2
726
79444
S217
G
I
K
L
Y
K
D
S
L
P
P
S
P
L
L
Chimpanzee
Pan troglodytes
XP_508046
726
79443
S217
G
I
K
L
Y
K
D
S
L
P
P
S
P
L
L
Rhesus Macaque
Macaca mulatta
XP_001091193
726
79615
S217
G
I
K
L
Y
K
D
S
L
P
P
S
P
L
L
Dog
Lupus familis
XP_544027
726
79345
S217
E
I
K
L
Y
K
D
S
L
P
P
S
P
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZW8
725
78412
S217
G
I
K
L
F
K
E
S
L
P
P
S
P
L
L
Rat
Rattus norvegicus
NP_001100914
725
78544
S217
G
I
K
L
F
K
E
S
L
P
P
S
P
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513492
831
90445
F217
V
I
K
L
Y
R
D
F
L
P
P
S
P
L
L
Chicken
Gallus gallus
Q5ZI67
727
79589
S212
G
I
K
L
Y
K
D
S
L
P
P
S
P
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036460
717
79762
D218
L
P
L
K
L
F
N
D
F
Q
P
A
S
N
L
Honey Bee
Apis mellifera
XP_396242
693
78148
D216
C
H
L
L
A
T
V
D
N
K
N
L
L
F
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795849
706
77013
T217
L
Y
P
G
K
V
T
T
N
P
E
G
T
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.6
90.7
N.A.
83.8
83.6
N.A.
69.4
75
N.A.
N.A.
N.A.
38.8
40.5
N.A.
46.8
Protein Similarity:
100
99.4
99.1
95.1
N.A.
90.9
90.6
N.A.
76.4
85.1
N.A.
N.A.
N.A.
55.7
59
N.A.
64.6
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
80
100
N.A.
N.A.
N.A.
13.3
6.6
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
100
N.A.
N.A.
N.A.
26.6
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
55
19
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
19
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
19
10
0
10
10
0
0
0
0
10
0
% F
% Gly:
55
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
73
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
73
10
10
64
0
0
0
10
0
0
0
0
0
% K
% Leu:
19
0
19
82
10
0
0
0
73
0
0
10
10
82
91
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
19
0
10
0
0
10
0
% N
% Pro:
0
10
10
0
0
0
0
0
0
82
82
0
73
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
64
0
0
0
73
10
0
0
% S
% Thr:
0
0
0
0
0
10
10
10
0
0
0
0
10
0
0
% T
% Val:
10
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
55
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _