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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NHLRC2 All Species: 13.64
Human Site: S624 Identified Species: 30
UniProt: Q8NBF2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBF2 NP_940916.2 726 79444 S624 K L R L D L P S G S K L T E G
Chimpanzee Pan troglodytes XP_508046 726 79443 S624 K L R L D L P S G S K L T E G
Rhesus Macaque Macaca mulatta XP_001091193 726 79615 S624 Q L R L D L P S G S K L T E G
Dog Lupus familis XP_544027 726 79345 S624 K L R L D L P S G T K L T E G
Cat Felis silvestris
Mouse Mus musculus Q8BZW8 725 78412 P623 R L K L Q L P P G A K L T E G
Rat Rattus norvegicus NP_001100914 725 78544 P623 G L R L E L P P G A K L T E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513492 831 90445 A625 G L R L V L P A K S K L T E E
Chicken Gallus gallus Q5ZI67 727 79589 P621 L L K L T L P P D S K L N E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036460 717 79762 P619 F F N L R L S P R F N F T K E
Honey Bee Apis mellifera XP_396242 693 78148 F597 N I S F N I I F F E R D L K L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795849 706 77013 P604 V L D V S L P P E S Y L T E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 97.6 90.7 N.A. 83.8 83.6 N.A. 69.4 75 N.A. N.A. N.A. 38.8 40.5 N.A. 46.8
Protein Similarity: 100 99.4 99.1 95.1 N.A. 90.9 90.6 N.A. 76.4 85.1 N.A. N.A. N.A. 55.7 59 N.A. 64.6
P-Site Identity: 100 100 93.3 93.3 N.A. 66.6 73.3 N.A. 66.6 53.3 N.A. N.A. N.A. 20 0 N.A. 53.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 73.3 60 N.A. N.A. N.A. 26.6 33.3 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 19 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 37 0 0 0 10 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 0 10 10 0 0 0 82 28 % E
% Phe: 10 10 0 10 0 0 0 10 10 10 0 10 0 0 0 % F
% Gly: 19 0 0 0 0 0 0 0 55 0 0 0 0 0 64 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 10 10 0 0 0 0 0 0 0 0 % I
% Lys: 28 0 19 0 0 0 0 0 10 0 73 0 0 19 0 % K
% Leu: 10 82 0 82 0 91 0 0 0 0 0 82 10 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 10 0 10 0 0 0 0 0 10 0 10 0 0 % N
% Pro: 0 0 0 0 0 0 82 46 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 55 0 10 0 0 0 10 0 10 0 0 0 0 % R
% Ser: 0 0 10 0 10 0 10 37 0 55 0 0 0 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 10 0 0 82 0 0 % T
% Val: 10 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _