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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NHLRC2
All Species:
22.73
Human Site:
T277
Identified Species:
50
UniProt:
Q8NBF2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBF2
NP_940916.2
726
79444
T277
D
G
I
F
S
E
S
T
F
N
S
P
Q
G
V
Chimpanzee
Pan troglodytes
XP_508046
726
79443
T277
D
G
I
F
S
E
S
T
F
N
S
P
Q
G
V
Rhesus Macaque
Macaca mulatta
XP_001091193
726
79615
T277
D
G
I
F
S
E
S
T
F
N
S
P
Q
G
V
Dog
Lupus familis
XP_544027
726
79345
T277
D
G
I
F
S
E
S
T
F
N
S
P
Q
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZW8
725
78412
S277
D
G
M
F
S
E
S
S
F
N
S
P
Q
G
V
Rat
Rattus norvegicus
NP_001100914
725
78544
S277
D
G
V
F
S
E
S
S
F
H
S
P
Q
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513492
831
90445
A277
D
G
T
F
S
E
S
A
F
N
S
P
Q
G
V
Chicken
Gallus gallus
Q5ZI67
727
79589
A272
D
G
R
F
S
E
A
A
F
N
S
P
Q
G
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036460
717
79762
R278
D
G
D
L
T
V
A
R
F
N
N
P
Q
G
I
Honey Bee
Apis mellifera
XP_396242
693
78148
R276
D
G
D
F
E
N
A
R
F
N
A
P
Q
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795849
706
77013
E283
V
I
Y
V
A
D
T
E
N
H
A
I
R
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.6
90.7
N.A.
83.8
83.6
N.A.
69.4
75
N.A.
N.A.
N.A.
38.8
40.5
N.A.
46.8
Protein Similarity:
100
99.4
99.1
95.1
N.A.
90.9
90.6
N.A.
76.4
85.1
N.A.
N.A.
N.A.
55.7
59
N.A.
64.6
P-Site Identity:
100
100
100
100
N.A.
86.6
80
N.A.
86.6
80
N.A.
N.A.
N.A.
46.6
60
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
N.A.
N.A.
73.3
73.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
28
19
0
0
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
91
0
19
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
73
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
82
0
0
0
0
91
0
0
0
0
0
0
% F
% Gly:
0
91
0
0
0
0
0
0
0
0
0
0
0
91
0
% G
% His:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% H
% Ile:
0
10
37
0
0
0
0
0
0
0
0
10
0
0
19
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
82
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
91
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
91
0
0
% Q
% Arg:
0
0
10
0
0
0
0
19
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
73
0
64
19
0
0
73
0
0
0
0
% S
% Thr:
0
0
10
0
10
0
10
37
0
0
0
0
0
0
0
% T
% Val:
10
0
10
10
0
10
0
0
0
0
0
0
0
0
82
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _