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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NHLRC2
All Species:
9.09
Human Site:
T664
Identified Species:
20
UniProt:
Q8NBF2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBF2
NP_940916.2
726
79444
T664
E
N
I
S
S
Q
P
T
I
S
L
Q
I
P
D
Chimpanzee
Pan troglodytes
XP_508046
726
79443
T664
E
N
I
S
S
Q
P
T
I
S
L
Q
I
P
D
Rhesus Macaque
Macaca mulatta
XP_001091193
726
79615
T664
E
N
I
S
S
Q
P
T
I
S
L
Q
I
P
D
Dog
Lupus familis
XP_544027
726
79345
A664
E
S
I
S
S
Q
P
A
I
S
L
Q
I
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZW8
725
78412
A663
E
N
I
S
N
Q
P
A
I
S
L
Q
I
P
T
Rat
Rattus norvegicus
NP_001100914
725
78544
A663
E
N
I
S
N
Q
P
A
I
S
L
Q
I
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513492
831
90445
E665
K
D
I
S
N
P
C
E
I
S
L
L
I
P
C
Chicken
Gallus gallus
Q5ZI67
727
79589
V662
K
D
V
S
C
Q
T
V
I
P
F
Q
L
P
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036460
717
79762
H655
N
L
L
D
G
M
C
H
M
Q
V
Q
A
T
R
Honey Bee
Apis mellifera
XP_396242
693
78148
E631
I
A
R
A
R
N
G
E
L
S
N
P
I
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795849
706
77013
P642
E
S
L
S
N
P
L
P
S
Y
T
W
T
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.6
90.7
N.A.
83.8
83.6
N.A.
69.4
75
N.A.
N.A.
N.A.
38.8
40.5
N.A.
46.8
Protein Similarity:
100
99.4
99.1
95.1
N.A.
90.9
90.6
N.A.
76.4
85.1
N.A.
N.A.
N.A.
55.7
59
N.A.
64.6
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
46.6
33.3
N.A.
N.A.
N.A.
6.6
13.3
N.A.
20
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
66.6
60
N.A.
N.A.
N.A.
26.6
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
28
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
10
0
19
0
0
0
0
0
0
0
10
% C
% Asp:
0
19
0
10
0
0
0
0
0
0
0
0
0
0
28
% D
% Glu:
64
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
0
64
0
0
0
0
0
73
0
0
0
73
0
10
% I
% Lys:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
19
0
0
0
10
0
10
0
64
10
10
0
0
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% M
% Asn:
10
46
0
0
37
10
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
19
55
10
0
10
0
10
0
82
10
% P
% Gln:
0
0
0
0
0
64
0
0
0
10
0
73
0
0
0
% Q
% Arg:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
19
% R
% Ser:
0
19
0
82
37
0
0
0
10
73
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
10
28
0
0
10
0
10
10
19
% T
% Val:
0
0
10
0
0
0
0
10
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _