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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NHLRC2
All Species:
30.91
Human Site:
Y490
Identified Species:
68
UniProt:
Q8NBF2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBF2
NP_940916.2
726
79444
Y490
D
K
K
R
N
L
L
Y
V
A
D
S
Y
N
H
Chimpanzee
Pan troglodytes
XP_508046
726
79443
Y490
D
K
K
R
N
L
L
Y
V
A
D
S
Y
N
H
Rhesus Macaque
Macaca mulatta
XP_001091193
726
79615
Y490
D
K
K
R
N
L
L
Y
V
A
D
S
Y
N
H
Dog
Lupus familis
XP_544027
726
79345
Y490
D
K
K
R
N
L
L
Y
V
A
D
S
Y
N
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZW8
725
78412
Y490
D
E
E
R
Q
V
L
Y
V
A
D
S
Y
N
H
Rat
Rattus norvegicus
NP_001100914
725
78544
Y490
D
E
K
R
H
L
L
Y
V
A
D
S
Y
N
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513492
831
90445
Y492
D
E
K
G
N
L
L
Y
V
A
D
S
Y
N
H
Chicken
Gallus gallus
Q5ZI67
727
79589
Y485
D
K
K
R
K
L
L
Y
V
A
D
S
Y
N
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036460
717
79762
L477
F
G
D
I
D
G
R
L
F
S
A
K
L
Q
H
Honey Bee
Apis mellifera
XP_396242
693
78148
K466
Y
G
D
S
D
G
I
K
Y
A
A
K
L
Q
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795849
706
77013
F470
W
D
H
S
K
L
L
F
V
A
D
S
Y
N
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.6
90.7
N.A.
83.8
83.6
N.A.
69.4
75
N.A.
N.A.
N.A.
38.8
40.5
N.A.
46.8
Protein Similarity:
100
99.4
99.1
95.1
N.A.
90.9
90.6
N.A.
76.4
85.1
N.A.
N.A.
N.A.
55.7
59
N.A.
64.6
P-Site Identity:
100
100
100
100
N.A.
73.3
86.6
N.A.
86.6
93.3
N.A.
N.A.
N.A.
6.6
13.3
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
20
26.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
91
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
73
10
19
0
19
0
0
0
0
0
82
0
0
0
0
% D
% Glu:
0
28
10
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% F
% Gly:
0
19
0
10
0
19
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
100
% H
% Ile:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
46
64
0
19
0
0
10
0
0
0
19
0
0
0
% K
% Leu:
0
0
0
0
0
73
82
10
0
0
0
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
46
0
0
0
0
0
0
0
0
82
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
19
0
% Q
% Arg:
0
0
0
64
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
19
0
0
0
0
0
10
0
82
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
82
0
0
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
73
10
0
0
0
82
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _