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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM178
All Species:
25.15
Human Site:
S147
Identified Species:
69.17
UniProt:
Q8NBL3
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBL3
NP_689603.1
297
33019
S147
T
A
I
K
Y
H
F
S
Q
P
I
R
L
R
N
Chimpanzee
Pan troglodytes
XP_527984
294
33390
S141
T
Y
I
K
Y
H
Y
S
S
A
T
I
P
R
N
Rhesus Macaque
Macaca mulatta
XP_001103558
239
26583
L94
H
F
S
Q
P
I
R
L
R
N
I
P
F
N
L
Dog
Lupus familis
XP_532944
367
40598
S217
T
A
I
K
Y
H
F
S
Q
P
I
R
L
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ16
297
33029
S147
T
A
I
K
Y
H
F
S
Q
P
I
R
L
R
N
Rat
Rattus norvegicus
Q68FV0
297
33061
S147
T
A
V
K
Y
H
F
S
Q
P
I
R
L
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509740
207
23141
R61
Y
H
F
S
Q
P
I
R
L
R
N
V
P
F
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5XGU1
304
34046
S154
T
A
I
K
Y
H
F
S
H
P
I
R
L
R
N
Zebra Danio
Brachydanio rerio
Q08CE6
301
33974
S151
T
S
V
K
Y
H
F
S
Q
P
I
R
L
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.1
80.4
80.1
N.A.
97.9
97.6
N.A.
56.9
N.A.
76.3
71.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
59.9
80.4
80.3
N.A.
98.9
98.9
N.A.
62.2
N.A.
84.5
82.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
6.6
100
N.A.
100
93.3
N.A.
6.6
N.A.
93.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
20
100
N.A.
100
100
N.A.
6.6
N.A.
93.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
56
0
0
0
0
0
0
0
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
12
12
0
0
0
67
0
0
0
0
0
12
12
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
12
12
0
0
0
78
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
56
0
0
12
12
0
0
0
78
12
0
0
0
% I
% Lys:
0
0
0
78
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
12
12
0
0
0
67
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
12
0
0
12
89
% N
% Pro:
0
0
0
0
12
12
0
0
0
67
0
12
23
0
0
% P
% Gln:
0
0
0
12
12
0
0
0
56
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
12
12
12
0
67
0
78
0
% R
% Ser:
0
12
12
12
0
0
0
78
12
0
0
0
0
0
0
% S
% Thr:
78
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% T
% Val:
0
0
23
0
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
12
0
0
78
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _