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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD17B11
All Species:
31.82
Human Site:
T140
Identified Species:
70
UniProt:
Q8NBQ5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBQ5
NP_057329.2
300
32936
T140
Q
D
P
Q
I
E
K
T
F
E
V
N
V
L
A
Chimpanzee
Pan troglodytes
XP_001157858
300
32945
T140
Q
D
P
Q
I
E
K
T
F
E
V
N
V
L
A
Rhesus Macaque
Macaca mulatta
XP_001096902
300
32948
T140
Q
D
A
Q
I
E
K
T
F
E
V
N
I
L
A
Dog
Lupus familis
XP_544970
300
33071
T140
Q
D
P
Q
I
E
K
T
F
E
V
N
V
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ06
298
32862
T140
Q
D
P
Q
I
E
K
T
F
E
V
N
V
L
A
Rat
Rattus norvegicus
Q6AYS8
298
32919
T140
Q
D
P
Q
I
E
K
T
F
E
V
N
V
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509870
297
32795
T140
Q
D
P
Q
I
Q
K
T
F
E
V
N
V
L
A
Chicken
Gallus gallus
XP_426310
299
32437
M140
Q
D
H
Q
I
E
K
M
F
E
V
N
I
L
A
Frog
Xenopus laevis
Q6DCT3
341
38425
T165
P
D
E
L
I
E
R
T
M
M
V
N
C
H
A
Zebra Danio
Brachydanio rerio
Q7T2D1
336
37801
T160
P
D
E
L
I
E
R
T
M
M
V
N
C
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05016
267
29140
V112
K
A
L
G
S
D
R
V
G
Q
I
A
T
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
94
84
N.A.
82.6
81
N.A.
77
62
39
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
97.6
92
N.A.
91.6
90.6
N.A.
88
76.6
54.2
55.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
100
N.A.
100
100
N.A.
93.3
80
46.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
100
86.6
53.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
0
0
0
0
10
0
0
91
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% C
% Asp:
0
91
0
0
0
10
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
19
0
0
82
0
0
0
73
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
19
0
% H
% Ile:
0
0
0
0
91
0
0
0
0
0
10
0
19
0
0
% I
% Lys:
10
0
0
0
0
0
73
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
19
0
0
0
0
0
0
0
0
0
73
0
% L
% Met:
0
0
0
0
0
0
0
10
19
19
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
91
0
0
0
% N
% Pro:
19
0
55
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
73
0
0
73
0
10
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
82
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
91
0
55
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _