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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM63B All Species: 14.24
Human Site: S587 Identified Species: 31.33
UniProt: Q8NBR6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBR6 NP_001035540.1 621 67106 S587 Q G Q P A Q A S P S S G R Q S
Chimpanzee Pan troglodytes XP_510443 621 67074 S587 Q G Q P A Q A S P S S G R Q S
Rhesus Macaque Macaca mulatta XP_001106845 328 36130 T300 Y H G L C E L T A A A K E D E
Dog Lupus familis XP_544702 619 67958 S586 Q S Q P A Q A S P S R R Q P G
Cat Felis silvestris
Mouse Mus musculus Q6PDI6 601 65618 S567 Q G Q P A Q A S P S S I K Q P
Rat Rattus norvegicus Q5BJQ2 482 52710 P453 Q P V R T R A P S S P G R G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506263 277 31353 C249 P G R Q E P G C G R H R T P R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A3KQS4 520 57347 A492 Q Q Q Q Q P S A G Q M R G Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_500023 379 42002 P351 P Q H R A P A P P A P Q T A R
Sea Urchin Strong. purpuratus XP_791130 551 60178 S523 P G Q R S S R S T P R P Q G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08930 360 41014 P332 K N S E I H A P V K K D K F K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 31.8 70 N.A. 83.4 44.6 N.A. 38.8 N.A. N.A. 43.6 N.A. N.A. N.A. 24.4 42
Protein Similarity: 100 100 39.9 73.7 N.A. 86.6 56.6 N.A. 40.7 N.A. N.A. 57.3 N.A. N.A. N.A. 39.9 57.4
P-Site Identity: 100 100 0 60 N.A. 80 33.3 N.A. 6.6 N.A. N.A. 20 N.A. N.A. N.A. 20 20
P-Site Similarity: 100 100 26.6 66.6 N.A. 86.6 46.6 N.A. 13.3 N.A. N.A. 40 N.A. N.A. N.A. 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 46 0 64 10 10 19 10 0 0 10 19 % A
% Cys: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % D
% Glu: 0 0 0 10 10 10 0 0 0 0 0 0 10 0 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 46 10 0 0 0 10 0 19 0 0 28 10 19 10 % G
% His: 0 10 10 0 0 10 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 10 10 10 19 0 10 % K
% Leu: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 28 10 0 37 0 28 0 28 46 10 19 10 0 19 10 % P
% Gln: 55 19 55 19 10 37 0 0 0 10 0 10 19 37 0 % Q
% Arg: 0 0 10 28 0 10 10 0 0 10 19 28 28 0 19 % R
% Ser: 0 10 10 0 10 10 10 46 10 46 28 0 0 0 19 % S
% Thr: 0 0 0 0 10 0 0 10 10 0 0 0 19 0 0 % T
% Val: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _