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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC4A11 All Species: 6.36
Human Site: T154 Identified Species: 14
UniProt: Q8NBS3 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBS3 NP_114423.1 891 99581 T154 S L D N V L R T M L R R F A R
Chimpanzee Pan troglodytes XP_514482 875 98108 N150 F A Q D P D N N E P N C N L D
Rhesus Macaque Macaca mulatta XP_001111005 913 101690 S176 S L D N V L R S M L Q R F A Q
Dog Lupus familis XP_542919 889 99137 A154 S L D D V L R A M L C R L A H
Cat Felis silvestris
Mouse Mus musculus A2AJN7 862 96732 L149 P D C D L D L L M A K L F T D
Rat Rattus norvegicus Q9JI66 1079 121325 M185 S L P Q L V E M I A D H Q I E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518886 256 28840
Chicken Gallus gallus P15575 922 102205 L175 E A E S V W T L P A A Q L Q C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001153300 846 95232 S151 N F E E I M S S L F T D A G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_495228 959 107963 K239 S L E E I F A K I I H E M D I
Sea Urchin Strong. purpuratus XP_784629 1012 112905 L190 S L E S I V T L L L A K M L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 94.5 79.9 N.A. 82.9 24.1 N.A. 26.7 24.2 N.A. 58.3 N.A. N.A. N.A. 36.8 39.2
Protein Similarity: 100 97.1 95.8 86.7 N.A. 89.4 41.8 N.A. 27.8 42 N.A. 72.9 N.A. N.A. N.A. 56.2 55
P-Site Identity: 100 0 80 66.6 N.A. 13.3 13.3 N.A. 0 6.6 N.A. 0 N.A. N.A. N.A. 13.3 20
P-Site Similarity: 100 6.6 100 73.3 N.A. 33.3 33.3 N.A. 0 26.6 N.A. 40 N.A. N.A. N.A. 40 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 0 0 0 10 10 0 28 19 0 10 28 10 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 10 10 0 0 10 % C
% Asp: 0 10 28 28 0 19 0 0 0 0 10 10 0 10 19 % D
% Glu: 10 0 37 19 0 0 10 0 10 0 0 10 0 0 10 % E
% Phe: 10 10 0 0 0 10 0 0 0 10 0 0 28 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 10 % H
% Ile: 0 0 0 0 28 0 0 0 19 10 0 0 0 10 10 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 10 10 0 0 0 % K
% Leu: 0 55 0 0 19 28 10 28 19 37 0 10 19 19 0 % L
% Met: 0 0 0 0 0 10 0 10 37 0 0 0 19 0 0 % M
% Asn: 10 0 0 19 0 0 10 10 0 0 10 0 10 0 0 % N
% Pro: 10 0 10 0 10 0 0 0 10 10 0 0 0 0 0 % P
% Gln: 0 0 10 10 0 0 0 0 0 0 10 10 10 10 10 % Q
% Arg: 0 0 0 0 0 0 28 0 0 0 10 28 0 0 10 % R
% Ser: 55 0 0 19 0 0 10 19 0 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 19 10 0 0 10 0 0 10 0 % T
% Val: 0 0 0 0 37 19 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _