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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXNDC5 All Species: 19.7
Human Site: S285 Identified Species: 27.08
UniProt: Q8NBS9 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBS9 NP_001139021.1 432 47629 S285 K G K R D L E S L R E Y V E S
Chimpanzee Pan troglodytes XP_001165912 391 44022 S244 K G K R D L E S L R E Y V E S
Rhesus Macaque Macaca mulatta XP_001085723 389 43644 S242 K G K R D L E S L R E Y V E L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q91W90 417 46397 S271 K G K R D L E S L R D Y V Q S
Rat Rattus norvegicus P38659 643 72702 P488 G K K F A M E P E E F D S D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514270 364 40832 E221 R D L D S L K E Y I D S Q L Q
Chicken Gallus gallus Q8JG64 505 56163 E339 D K F V M Q E E F S R D G K A
Frog Xenopus laevis Q6NRT6 796 90966 I416 S I C S E L Y I H K P C V A A
Zebra Danio Brachydanio rerio NP_998181 327 37321 D184 D S F K E F V D N H V K A A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572742 416 46632 T262 S G A R D L S T L K T Y V E K
Honey Bee Apis mellifera XP_392102 374 42835 G227 K K V D K Y T G Q R T H E E L
Nematode Worm Caenorhab. elegans P34329 618 69779 F464 Y P M N P D E F D G E L D E N
Sea Urchin Strong. purpuratus XP_001201177 398 44341 A243 K G G R D H V A M K E Y V S K
Poplar Tree Populus trichocarpa XP_002320314 358 39382 S215 L A E K Y G V S G F P T L K F
Maize Zea mays NP_001105759 366 40038 F223 E K Y G V S G F P T L K F F P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22263 361 39478 T218 Y G V S G F P T L K F F P K D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q92249 369 39263 G226 T I K F F P K G S T T P E D Y
Conservation
Percent
Protein Identity: 100 75.6 79.6 N.A. N.A. 84 23 N.A. 64.1 22.7 20.8 49.7 N.A. 41.9 41.6 24.6 44.2
Protein Similarity: 100 80.3 82.1 N.A. N.A. 88.8 35.2 N.A. 72.2 38.2 31 62.9 N.A. 57.4 57.1 38 59.2
P-Site Identity: 100 100 93.3 N.A. N.A. 86.6 13.3 N.A. 6.6 6.6 13.3 0 N.A. 53.3 20 20 46.6
P-Site Similarity: 100 100 93.3 N.A. N.A. 100 33.3 N.A. 26.6 20 33.3 13.3 N.A. 66.6 26.6 26.6 66.6
Percent
Protein Identity: 26.6 28.2 N.A. 26.3 N.A. 27.5
Protein Similarity: 41.9 41.6 N.A. 41.9 N.A. 41.2
P-Site Identity: 6.6 0 N.A. 13.3 N.A. 6.6
P-Site Similarity: 33.3 6.6 N.A. 40 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 6 0 6 0 0 6 0 0 0 0 6 12 18 % A
% Cys: 0 0 6 0 0 0 0 0 0 0 0 6 0 0 0 % C
% Asp: 12 6 0 12 36 6 0 6 6 0 12 12 6 12 6 % D
% Glu: 6 0 6 0 12 0 42 12 6 6 30 0 12 36 6 % E
% Phe: 0 0 12 12 6 12 0 12 6 6 12 6 6 6 6 % F
% Gly: 6 42 6 6 6 6 6 12 6 6 0 0 6 0 0 % G
% His: 0 0 0 0 0 6 0 0 6 6 0 6 0 0 0 % H
% Ile: 0 12 0 0 0 0 0 6 0 6 0 0 0 0 0 % I
% Lys: 36 24 36 12 6 0 12 0 0 24 0 12 0 18 12 % K
% Leu: 6 0 6 0 0 42 0 0 36 0 6 6 6 6 12 % L
% Met: 0 0 6 0 6 6 0 0 6 0 0 0 0 0 0 % M
% Asn: 0 0 0 6 0 0 0 0 6 0 0 0 0 0 6 % N
% Pro: 0 6 0 0 6 6 6 6 6 0 12 6 6 0 6 % P
% Gln: 0 0 0 0 0 6 0 0 6 0 0 0 6 6 6 % Q
% Arg: 6 0 0 36 0 0 0 0 0 30 6 0 0 0 0 % R
% Ser: 12 6 0 12 6 6 6 30 6 6 0 6 6 6 18 % S
% Thr: 6 0 0 0 0 0 6 12 0 12 18 6 0 0 0 % T
% Val: 0 0 12 6 6 0 18 0 0 0 6 0 42 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 0 6 0 6 6 6 0 6 0 0 36 0 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _