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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXNDC5 All Species: 2.12
Human Site: S426 Identified Species: 2.92
UniProt: Q8NBS9 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBS9 NP_001139021.1 432 47629 S426 S L H R F V L S Q A K D E L _
Chimpanzee Pan troglodytes XP_001165912 391 44022 G385 S L H R F V L G Q A K D E L _
Rhesus Macaque Macaca mulatta XP_001085723 389 43644 G383 S L H R F V L G Q A K D E L _
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q91W90 417 46397 R411 S L H S F V L R Q A K D E L _
Rat Rattus norvegicus P38659 643 72702 F628 D L E H L S K F I D E H A T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514270 364 40832
Chicken Gallus gallus Q8JG64 505 56163 L478 V S D F I S Y L K R E A T S T
Frog Xenopus laevis Q6NRT6 796 90966 A774 S R D A K E I A Q I I T K R I
Zebra Danio Brachydanio rerio NP_998181 327 37321
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572742 416 46632 K409 E L Q A Y L K K F L G H D E L
Honey Bee Apis mellifera XP_392102 374 42835 I366 D L Y E F I M I Y V Q P H D E
Nematode Worm Caenorhab. elegans P34329 618 69779 M604 L E D L K K F M T K H G V K S
Sea Urchin Strong. purpuratus XP_001201177 398 44341 S391 A L E T Y L K S K L P K E E L
Poplar Tree Populus trichocarpa XP_002320314 358 39382
Maize Zea mays NP_001105759 366 40038
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22263 361 39478
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q92249 369 39263
Conservation
Percent
Protein Identity: 100 75.6 79.6 N.A. N.A. 84 23 N.A. 64.1 22.7 20.8 49.7 N.A. 41.9 41.6 24.6 44.2
Protein Similarity: 100 80.3 82.1 N.A. N.A. 88.8 35.2 N.A. 72.2 38.2 31 62.9 N.A. 57.4 57.1 38 59.2
P-Site Identity: 100 92.8 92.8 N.A. N.A. 85.7 6.6 N.A. 0 0 13.3 0 N.A. 6.6 13.3 0 20
P-Site Similarity: 100 92.8 92.8 N.A. N.A. 85.7 13.3 N.A. 0 13.3 40 0 N.A. 26.6 40 0 46.6
Percent
Protein Identity: 26.6 28.2 N.A. 26.3 N.A. 27.5
Protein Similarity: 41.9 41.6 N.A. 41.9 N.A. 41.2
P-Site Identity: 0 0 N.A. 0 N.A. 0
P-Site Similarity: 0 0 N.A. 0 N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 12 0 0 0 6 0 24 0 6 6 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 18 0 0 0 0 0 0 6 0 24 6 6 0 % D
% Glu: 6 6 12 6 0 6 0 0 0 0 12 0 30 12 6 % E
% Phe: 0 0 0 6 30 0 6 6 6 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 12 0 0 6 6 0 0 0 % G
% His: 0 0 24 6 0 0 0 0 0 0 6 12 6 0 0 % H
% Ile: 0 0 0 0 6 6 6 6 6 6 6 0 0 0 6 % I
% Lys: 0 0 0 0 12 6 18 6 12 6 24 6 6 6 6 % K
% Leu: 6 48 0 6 6 12 24 6 0 12 0 0 0 24 12 % L
% Met: 0 0 0 0 0 0 6 6 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 6 6 0 0 0 % P
% Gln: 0 0 6 0 0 0 0 0 30 0 6 0 0 0 0 % Q
% Arg: 0 6 0 18 0 0 0 6 0 6 0 0 0 6 0 % R
% Ser: 30 6 0 6 0 12 0 12 0 0 0 0 0 6 6 % S
% Thr: 0 0 0 6 0 0 0 0 6 0 0 6 6 6 6 % T
% Val: 6 0 0 0 0 24 0 0 0 6 0 0 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 12 0 6 0 6 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24 % _