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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXNDC5 All Species: 10.3
Human Site: T304 Identified Species: 14.17
UniProt: Q8NBS9 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBS9 NP_001139021.1 432 47629 T304 T E T G A T E T V T P S E A P
Chimpanzee Pan troglodytes XP_001165912 391 44022 T263 T A T G A T E T V T P S E A P
Rhesus Macaque Macaca mulatta XP_001085723 389 43644 T261 T E T G A T E T V K P S E A P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q91W90 417 46397 V290 S E A A P E T V E P S E A P V
Rat Rattus norvegicus P38659 643 72702 K507 V M A F K K G K L K P V I K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514270 364 40832 S240 A P E A P K P S E I P P E G A
Chicken Gallus gallus Q8JG64 505 56163 N358 L Q D Y F D G N L K K Y L K S
Frog Xenopus laevis Q6NRT6 796 90966 H435 G I S A Y E I H H G K V Q L Y
Zebra Danio Brachydanio rerio NP_998181 327 37321 T203 P E K E E E H T H E I P P S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572742 416 46632 E281 P L E K T A G E A G D E K V V
Honey Bee Apis mellifera XP_392102 374 42835 N246 S K M L E K E N D Q M D T K T
Nematode Worm Caenorhab. elegans P34329 618 69779 K483 M K Q I S S G K A K A H V K S
Sea Urchin Strong. purpuratus XP_001201177 398 44341 G262 A E A A P L P G S E E A I K V
Poplar Tree Populus trichocarpa XP_002320314 358 39382 E234 N K A G E D Y E G G R D L D D
Maize Zea mays NP_001105759 366 40038 G242 A G E D Y D G G R D L D D F V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22263 361 39478 D237 H D Y D G G R D L D D F V S F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q92249 369 39263 F245 S E A D L V K F L N E K A G T
Conservation
Percent
Protein Identity: 100 75.6 79.6 N.A. N.A. 84 23 N.A. 64.1 22.7 20.8 49.7 N.A. 41.9 41.6 24.6 44.2
Protein Similarity: 100 80.3 82.1 N.A. N.A. 88.8 35.2 N.A. 72.2 38.2 31 62.9 N.A. 57.4 57.1 38 59.2
P-Site Identity: 100 93.3 93.3 N.A. N.A. 6.6 6.6 N.A. 13.3 0 0 13.3 N.A. 0 6.6 0 6.6
P-Site Similarity: 100 93.3 93.3 N.A. N.A. 13.3 13.3 N.A. 20 13.3 13.3 20 N.A. 6.6 20 20 13.3
Percent
Protein Identity: 26.6 28.2 N.A. 26.3 N.A. 27.5
Protein Similarity: 41.9 41.6 N.A. 41.9 N.A. 41.2
P-Site Identity: 6.6 0 N.A. 0 N.A. 6.6
P-Site Similarity: 13.3 6.6 N.A. 20 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 18 6 30 24 18 6 0 0 12 0 6 6 12 18 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 6 18 0 18 0 6 6 12 12 18 6 6 6 % D
% Glu: 0 36 18 6 18 18 24 12 12 12 12 12 24 0 0 % E
% Phe: 0 0 0 6 6 0 0 6 0 0 0 6 0 6 6 % F
% Gly: 6 6 0 24 6 6 30 12 6 18 0 0 0 12 0 % G
% His: 6 0 0 0 0 0 6 6 12 0 0 6 0 0 0 % H
% Ile: 0 6 0 6 0 0 6 0 0 6 6 0 12 0 0 % I
% Lys: 0 18 6 6 6 18 6 12 0 24 12 6 6 30 0 % K
% Leu: 6 6 0 6 6 6 0 0 24 0 6 0 12 6 0 % L
% Met: 6 6 6 0 0 0 0 0 0 0 6 0 0 0 0 % M
% Asn: 6 0 0 0 0 0 0 12 0 6 0 0 0 0 0 % N
% Pro: 12 6 0 0 18 0 12 0 0 6 30 12 6 6 18 % P
% Gln: 0 6 6 0 0 0 0 0 0 6 0 0 6 0 0 % Q
% Arg: 0 0 0 0 0 0 6 0 6 0 6 0 0 0 0 % R
% Ser: 18 0 6 0 6 6 0 6 6 0 6 18 0 12 18 % S
% Thr: 18 0 18 0 6 18 6 24 0 12 0 0 6 0 12 % T
% Val: 6 0 0 0 0 6 0 6 18 0 0 12 12 6 24 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 6 12 0 6 0 0 0 0 6 0 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _