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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXNDC5 All Species: 13.94
Human Site: Y192 Identified Species: 19.17
UniProt: Q8NBS9 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBS9 NP_001139021.1 432 47629 Y192 P E L K Q G L Y E L S A S N F
Chimpanzee Pan troglodytes XP_001165912 391 44022 Y151 P E L K Q G L Y E L S A S N F
Rhesus Macaque Macaca mulatta XP_001085723 389 43644 Y149 P E L K Q G L Y E L S A S N F
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q91W90 417 46397 Y178 P E L K Q G L Y E L S A N N F
Rat Rattus norvegicus P38659 643 72702 I306 K D G D D V V I L G V F Q G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514270 364 40832 F142 H T T T G N H F I K F F A P W
Chicken Gallus gallus Q8JG64 505 56163 V154 I G D K D A S V V G F F R D A
Frog Xenopus laevis Q6NRT6 796 90966 V258 E D A F S S G V G W L I T F C
Zebra Danio Brachydanio rerio NP_998181 327 37321 F105 K G S H F V K F F A P W C G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572742 416 46632 K167 V E N L N I G K V V D L T E D
Honey Bee Apis mellifera XP_392102 374 42835 F147 L E L T E D N F D K H V S S G
Nematode Worm Caenorhab. elegans P34329 618 69779 S162 E N F D D F I S N N E L V L V
Sea Urchin Strong. purpuratus XP_001201177 398 44341 T156 L Y E L T V A T F K D H V A K
Poplar Tree Populus trichocarpa XP_002320314 358 39382 K136 T E G G T N V K I A A V P S N
Maize Zea mays NP_001105759 366 40038 A144 A G T N V K I A A I P S S V V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22263 361 39478 V139 T N V K L A A V P Q N V V V L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q92249 369 39263 N147 P S L V N I L N D A T I K G A
Conservation
Percent
Protein Identity: 100 75.6 79.6 N.A. N.A. 84 23 N.A. 64.1 22.7 20.8 49.7 N.A. 41.9 41.6 24.6 44.2
Protein Similarity: 100 80.3 82.1 N.A. N.A. 88.8 35.2 N.A. 72.2 38.2 31 62.9 N.A. 57.4 57.1 38 59.2
P-Site Identity: 100 100 100 N.A. N.A. 93.3 0 N.A. 0 6.6 0 0 N.A. 6.6 20 0 0
P-Site Similarity: 100 100 100 N.A. N.A. 100 13.3 N.A. 20 13.3 13.3 6.6 N.A. 20 46.6 6.6 0
Percent
Protein Identity: 26.6 28.2 N.A. 26.3 N.A. 27.5
Protein Similarity: 41.9 41.6 N.A. 41.9 N.A. 41.2
P-Site Identity: 6.6 6.6 N.A. 6.6 N.A. 20
P-Site Similarity: 26.6 26.6 N.A. 20 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 6 0 0 12 12 6 6 18 6 24 6 6 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 6 % C
% Asp: 0 12 6 12 18 6 0 0 12 0 12 0 0 6 6 % D
% Glu: 12 42 6 0 6 0 0 0 24 0 6 0 0 6 0 % E
% Phe: 0 0 6 6 6 6 0 18 12 0 12 18 0 6 24 % F
% Gly: 0 18 12 6 6 24 12 0 6 12 0 0 0 18 6 % G
% His: 6 0 0 6 0 0 6 0 0 0 6 6 0 0 6 % H
% Ile: 6 0 0 0 0 12 12 6 12 6 0 12 0 0 0 % I
% Lys: 12 0 0 36 0 6 6 12 0 18 0 0 6 0 6 % K
% Leu: 12 0 36 12 6 0 30 0 6 24 6 12 0 6 6 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 6 6 12 12 6 6 6 6 6 0 6 24 6 % N
% Pro: 30 0 0 0 0 0 0 0 6 0 12 0 6 6 0 % P
% Gln: 0 0 0 0 24 0 0 0 0 6 0 0 6 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % R
% Ser: 0 6 6 0 6 6 6 6 0 0 24 6 30 12 0 % S
% Thr: 12 6 12 12 12 0 0 6 0 0 6 0 12 0 0 % T
% Val: 6 0 6 6 6 18 12 18 12 6 6 18 18 12 18 % V
% Trp: 0 0 0 0 0 0 0 0 0 6 0 6 0 0 6 % W
% Tyr: 0 6 0 0 0 0 0 24 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _