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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR51A All Species: 30.61
Human Site: T246 Identified Species: 48.1
UniProt: Q8NBT0 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBT0 NP_001155052.1 407 45009 T246 P S G N Y L I T A S S D S T L
Chimpanzee Pan troglodytes XP_001166187 478 53623 T245 P S G N Y L I T A S S D G T L
Rhesus Macaque Macaca mulatta XP_001086686 541 59031 T380 P S G N Y L I T A S S D S T L
Dog Lupus familis XP_541857 406 45131 T246 P S G N Y L L T A S S D S T L
Cat Felis silvestris
Mouse Mus musculus Q8JZX3 405 45107 T246 P S G N Y L I T A S S D S T L
Rat Rattus norvegicus Q4V8C4 328 36030 C175 I S A V H F H C N G S L I V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511254 538 59486 T257 P S G N Y L I T A S S D G T L
Chicken Gallus gallus XP_414244 457 50965 T297 P S G N Y L I T A S N D S T L
Frog Xenopus laevis Q5FWQ6 415 45899 I248 H T V S V W E I P S G R R I H
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres NP_001163823 356 39390 L203 T V K I L D L L E G R L M Y T
Fruit Fly Dros. melanogaster Q9V3J8 361 39023 R208 V S A V H F N R D G S L I V S
Honey Bee Apis mellifera XP_624420 406 45441 T245 P K G N F I L T A S D D S T M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus O61585 690 75795 C244 P D G S Y L F C S S Q D M L H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O24456 327 35729 K174 I V S A S W D K T V K V W N L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q01369 316 35112 P163 F S P N P Q N P V I V S S G W
Conservation
Percent
Protein Identity: 100 51.6 73.5 93.3 N.A. 90.4 24.8 N.A. 40.5 66.3 23.6 N.A. 49.1 26.5 41.2 N.A. 21.7
Protein Similarity: 100 67.7 73.9 96.3 N.A. 94.8 44.4 N.A. 56.3 75 40.4 N.A. 66.3 43.4 60.9 N.A. 33.6
P-Site Identity: 100 93.3 100 93.3 N.A. 100 13.3 N.A. 93.3 93.3 6.6 N.A. 0 13.3 60 N.A. 40
P-Site Similarity: 100 93.3 100 100 N.A. 100 20 N.A. 93.3 100 20 N.A. 6.6 20 86.6 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 23.8 N.A. 24
Protein Similarity: N.A. N.A. N.A. 38.3 N.A. 41.2
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 20
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 7 0 0 0 0 54 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 7 7 0 7 0 7 60 0 0 0 % D
% Glu: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % E
% Phe: 7 0 0 0 7 14 7 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 60 0 0 0 0 0 0 20 7 0 14 7 0 % G
% His: 7 0 0 0 14 0 7 0 0 0 0 0 0 0 14 % H
% Ile: 14 0 0 7 0 7 40 7 0 7 0 0 14 7 0 % I
% Lys: 0 7 7 0 0 0 0 7 0 0 7 0 0 0 0 % K
% Leu: 0 0 0 0 7 54 20 7 0 0 0 20 0 7 54 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 14 0 7 % M
% Asn: 0 0 0 60 0 0 14 0 7 0 7 0 0 7 0 % N
% Pro: 60 0 7 0 7 0 0 7 7 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 7 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 7 0 0 7 7 7 0 0 % R
% Ser: 0 67 7 14 7 0 0 0 7 67 54 7 47 0 14 % S
% Thr: 7 7 0 0 0 0 0 54 7 0 0 0 0 54 7 % T
% Val: 7 14 7 14 7 0 0 0 7 7 7 7 0 14 0 % V
% Trp: 0 0 0 0 0 14 0 0 0 0 0 0 7 0 7 % W
% Tyr: 0 0 0 0 54 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _