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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM145
All Species:
20
Human Site:
T456
Identified Species:
44
UniProt:
Q8NBT3
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBT3
NP_775904.2
493
55604
T456
S
D
S
V
P
N
F
T
E
L
F
S
I
P
P
Chimpanzee
Pan troglodytes
XP_001142679
487
54558
T450
S
D
S
V
P
N
F
T
E
L
F
S
I
P
P
Rhesus Macaque
Macaca mulatta
XP_001097777
479
53690
T442
S
D
S
V
P
N
F
T
E
L
F
S
I
P
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8C4U2
746
82455
T470
S
D
S
V
P
N
F
T
E
L
F
S
I
P
P
Rat
Rattus norvegicus
XP_002725596
493
55754
T456
S
D
S
V
P
N
F
T
E
L
F
S
I
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517646
125
14239
L98
F
A
V
P
V
M
A
L
I
A
N
F
G
I
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U239
547
61735
S463
E
L
F
S
I
P
S
S
N
G
S
S
A
G
I
Zebra Danio
Brachydanio rerio
XP_686062
369
41174
S342
P
P
R
S
S
A
H
S
P
P
P
P
P
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120120
421
48474
Q394
M
P
I
G
G
E
G
Q
D
H
S
Y
E
P
N
Nematode Worm
Caenorhab. elegans
NP_510017
513
59248
T482
M
H
G
V
I
E
L
T
V
T
N
M
N
T
P
Sea Urchin
Strong. purpuratus
XP_001200832
438
49887
N411
A
Q
N
P
P
N
G
N
T
N
G
M
V
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
92.4
N.A.
N.A.
64
96.5
N.A.
24.3
N.A.
68.5
49.7
N.A.
N.A.
30.4
29.2
35.5
Protein Similarity:
100
94.1
93.7
N.A.
N.A.
64.6
97.5
N.A.
24.7
N.A.
75.1
55.7
N.A.
N.A.
46.8
49.1
50.9
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
6.6
N.A.
6.6
0
N.A.
N.A.
6.6
20
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
6.6
N.A.
13.3
6.6
N.A.
N.A.
13.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
10
10
0
0
10
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
46
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
19
0
0
46
0
0
0
10
0
0
% E
% Phe:
10
0
10
0
0
0
46
0
0
0
46
10
0
0
0
% F
% Gly:
0
0
10
10
10
0
19
0
0
10
10
0
10
10
10
% G
% His:
0
10
0
0
0
0
10
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
19
0
0
0
10
0
0
0
46
10
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
10
10
0
46
0
0
0
0
10
% L
% Met:
19
0
0
0
0
10
0
0
0
0
0
19
0
0
0
% M
% Asn:
0
0
10
0
0
55
0
10
10
10
19
0
10
10
10
% N
% Pro:
10
19
0
19
55
10
0
0
10
10
10
10
10
55
64
% P
% Gln:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
46
0
46
19
10
0
10
19
0
0
19
55
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
55
10
10
0
0
0
10
0
% T
% Val:
0
0
10
55
10
0
0
0
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _