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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCCPDH
All Species:
26.67
Human Site:
S254
Identified Species:
53.33
UniProt:
Q8NBX0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBX0
NP_057086.2
429
47151
S254
P
F
M
G
S
D
V
S
V
V
R
R
T
Q
R
Chimpanzee
Pan troglodytes
XP_525121
429
47073
S254
P
F
M
G
S
D
V
S
V
V
R
R
T
Q
R
Rhesus Macaque
Macaca mulatta
XP_001088347
181
19807
V24
E
N
L
E
E
S
P
V
Q
Y
A
A
Y
V
T
Dog
Lupus familis
XP_537227
382
41646
V225
E
N
L
E
Q
S
P
V
Q
Y
A
A
Y
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R127
429
47111
S254
P
F
L
G
S
D
I
S
V
V
K
R
T
Q
R
Rat
Rattus norvegicus
Q6AY30
429
47070
S254
P
F
L
G
S
D
M
S
V
V
K
R
T
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515055
430
47273
S255
P
F
M
G
A
D
A
S
V
V
R
R
T
Q
R
Chicken
Gallus gallus
NP_001012893
434
46837
S259
P
F
M
G
S
D
V
S
V
V
K
R
S
Q
R
Frog
Xenopus laevis
NP_001086196
429
46612
A254
P
F
L
G
A
D
S
A
V
V
R
R
T
Q
R
Zebra Danio
Brachydanio rerio
NP_001002359
427
46270
S257
P
F
I
G
T
D
P
S
V
V
K
R
T
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624456
422
47396
E254
R
T
Q
R
F
L
Y
E
K
Y
K
Q
R
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LGI2
454
49663
V255
K
L
P
S
A
D
A
V
V
V
R
R
T
L
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
41
77.8
N.A.
87.1
85.7
N.A.
77.6
68.6
67.3
60.8
N.A.
N.A.
41.4
N.A.
N.A.
Protein Similarity:
100
99.3
41.7
82.9
N.A.
94.4
94.6
N.A.
87.2
81.1
81.3
77.8
N.A.
N.A.
62
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
80
80
N.A.
86.6
86.6
73.3
73.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
6.6
6.6
N.A.
100
100
N.A.
93.3
100
93.3
93.3
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
25
0
17
9
0
0
17
17
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
0
% D
% Glu:
17
0
0
17
9
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
67
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
9
0
42
0
0
0
0
% K
% Leu:
0
9
42
0
0
9
0
0
0
0
0
0
0
9
0
% L
% Met:
0
0
34
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
67
0
9
0
0
0
25
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
9
0
9
0
0
0
17
0
0
9
0
67
0
% Q
% Arg:
9
0
0
9
0
0
0
0
0
0
42
75
9
0
67
% R
% Ser:
0
0
0
9
42
17
9
59
0
0
0
0
9
0
0
% S
% Thr:
0
9
0
0
9
0
0
0
0
0
0
0
67
0
25
% T
% Val:
0
0
0
0
0
0
25
25
75
75
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
25
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _