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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCCPDH All Species: 22.42
Human Site: S346 Identified Species: 44.85
UniProt: Q8NBX0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBX0 NP_057086.2 429 47151 S346 T F F G Q G Y S Q G T G T D K
Chimpanzee Pan troglodytes XP_525121 429 47073 S346 T F F G Q G Y S Q G T S A D K
Rhesus Macaque Macaca mulatta XP_001088347 181 19807 Q99 F F G Q G Y S Q G L G T D K N
Dog Lupus familis XP_537227 382 41646 Q300 F F G Q G Y S Q G F G P E K N
Cat Felis silvestris
Mouse Mus musculus Q8R127 429 47111 S346 T F F G Q G Y S H G T C V E K
Rat Rattus norvegicus Q6AY30 429 47070 S346 T F F G Q G Y S H G V S A E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515055 430 47273 S347 T F F G Q G Y S H G H S P K H
Chicken Gallus gallus NP_001012893 434 46837 S351 T F F G E G Y S E G Q D P Q S
Frog Xenopus laevis NP_001086196 429 46612 S346 T F F G E G Y S Q G H N P Q D
Zebra Danio Brachydanio rerio NP_001002359 427 46270 G345 S F H I L F F G D G Y T K G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624456 422 47396 V339 E G W T E K L V E P T D K H K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LGI2 454 49663 S368 W F I G R G Y S E E S L A S Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 41 77.8 N.A. 87.1 85.7 N.A. 77.6 68.6 67.3 60.8 N.A. N.A. 41.4 N.A. N.A.
Protein Similarity: 100 99.3 41.7 82.9 N.A. 94.4 94.6 N.A. 87.2 81.1 81.3 77.8 N.A. N.A. 62 N.A. N.A.
P-Site Identity: 100 86.6 6.6 6.6 N.A. 73.3 66.6 N.A. 60 53.3 60 13.3 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 86.6 6.6 6.6 N.A. 80 73.3 N.A. 60 66.6 66.6 33.3 N.A. N.A. 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 35.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 59.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 17 9 17 9 % D
% Glu: 9 0 0 0 25 0 0 0 25 9 0 0 9 17 0 % E
% Phe: 17 92 59 0 0 9 9 0 0 9 0 0 0 0 0 % F
% Gly: 0 9 17 67 17 67 0 9 17 67 17 9 0 9 0 % G
% His: 0 0 9 0 0 0 0 0 25 0 17 0 0 9 9 % H
% Ile: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 0 0 17 25 42 % K
% Leu: 0 0 0 0 9 0 9 0 0 9 0 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 17 % N
% Pro: 0 0 0 0 0 0 0 0 0 9 0 9 25 0 0 % P
% Gln: 0 0 0 17 42 0 0 17 25 0 9 0 0 17 17 % Q
% Arg: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 0 0 0 0 17 67 0 0 9 25 0 9 9 % S
% Thr: 59 0 0 9 0 0 0 0 0 0 34 17 9 0 0 % T
% Val: 0 0 0 0 0 0 0 9 0 0 9 0 9 0 0 % V
% Trp: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 17 67 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _