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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCCPDH
All Species:
23.64
Human Site:
Y345
Identified Species:
47.27
UniProt:
Q8NBX0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBX0
NP_057086.2
429
47151
Y345
L
T
F
F
G
Q
G
Y
S
Q
G
T
G
T
D
Chimpanzee
Pan troglodytes
XP_525121
429
47073
Y345
L
T
F
F
G
Q
G
Y
S
Q
G
T
S
A
D
Rhesus Macaque
Macaca mulatta
XP_001088347
181
19807
S98
T
F
F
G
Q
G
Y
S
Q
G
L
G
T
D
K
Dog
Lupus familis
XP_537227
382
41646
S299
T
F
F
G
Q
G
Y
S
Q
G
F
G
P
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R127
429
47111
Y345
M
T
F
F
G
Q
G
Y
S
H
G
T
C
V
E
Rat
Rattus norvegicus
Q6AY30
429
47070
Y345
M
T
F
F
G
Q
G
Y
S
H
G
V
S
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515055
430
47273
Y346
F
T
F
F
G
Q
G
Y
S
H
G
H
S
P
K
Chicken
Gallus gallus
NP_001012893
434
46837
Y350
M
T
F
F
G
E
G
Y
S
E
G
Q
D
P
Q
Frog
Xenopus laevis
NP_001086196
429
46612
Y345
M
T
F
F
G
E
G
Y
S
Q
G
H
N
P
Q
Zebra Danio
Brachydanio rerio
NP_001002359
427
46270
F344
A
S
F
H
I
L
F
F
G
D
G
Y
T
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624456
422
47396
L338
A
E
G
W
T
E
K
L
V
E
P
T
D
K
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LGI2
454
49663
Y367
M
W
F
I
G
R
G
Y
S
E
E
S
L
A
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
41
77.8
N.A.
87.1
85.7
N.A.
77.6
68.6
67.3
60.8
N.A.
N.A.
41.4
N.A.
N.A.
Protein Similarity:
100
99.3
41.7
82.9
N.A.
94.4
94.6
N.A.
87.2
81.1
81.3
77.8
N.A.
N.A.
62
N.A.
N.A.
P-Site Identity:
100
86.6
6.6
6.6
N.A.
66.6
60
N.A.
60
53.3
60
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
86.6
6.6
6.6
N.A.
80
73.3
N.A.
60
73.3
73.3
26.6
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
0
0
0
0
0
0
0
0
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
17
9
17
% D
% Glu:
0
9
0
0
0
25
0
0
0
25
9
0
0
9
17
% E
% Phe:
9
17
92
59
0
0
9
9
0
0
9
0
0
0
0
% F
% Gly:
0
0
9
17
67
17
67
0
9
17
67
17
9
0
9
% G
% His:
0
0
0
9
0
0
0
0
0
25
0
17
0
0
9
% H
% Ile:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
0
17
25
% K
% Leu:
17
0
0
0
0
9
0
9
0
0
9
0
9
0
0
% L
% Met:
42
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
0
9
25
0
% P
% Gln:
0
0
0
0
17
42
0
0
17
25
0
9
0
0
17
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
0
0
0
0
17
67
0
0
9
25
0
9
% S
% Thr:
17
59
0
0
9
0
0
0
0
0
0
34
17
9
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
9
0
9
0
% V
% Trp:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
17
67
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _