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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INO80E All Species: 20
Human Site: S109 Identified Species: 44
UniProt: Q8NBZ0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBZ0 NP_775889.1 244 26478 S109 G G A P S P S S L S L P P S T
Chimpanzee Pan troglodytes XP_001147129 244 26500 S109 G G T P S P S S L S L P P S T
Rhesus Macaque Macaca mulatta XP_001107210 244 26440 S109 G G A P S P S S L S L P P S T
Dog Lupus familis XP_547064 244 26306 S109 G G A P S P S S L S L P P S T
Cat Felis silvestris
Mouse Mus musculus NP_705808 205 21414 P97 Y L S S L A S P P Y P P F P S
Rat Rattus norvegicus Q6AYH2 244 26339 S109 G G A P S P S S L S L P P S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521309 217 23076 S107 P Y L S S L A S P P Y H P F P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_991199 231 25428 H109 V P S S S S P H L S L L S R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_724986 291 31580 I154 K D K G A P G I P G V P P H M
Honey Bee Apis mellifera XP_393482 236 27020 H122 G I S N H T P H H I P T V T K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793894 280 31387 T114 P T K K L M G T P V L G A S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 99.1 96.7 N.A. 75.8 94.2 N.A. 78.6 N.A. N.A. 47.9 N.A. 25.7 35.2 N.A. 34.2
Protein Similarity: 100 99.1 99.1 96.7 N.A. 77.4 95.4 N.A. 81.9 N.A. N.A. 60.6 N.A. 38.4 49.1 N.A. 47.1
P-Site Identity: 100 93.3 100 100 N.A. 13.3 93.3 N.A. 20 N.A. N.A. 26.6 N.A. 20 6.6 N.A. 13.3
P-Site Similarity: 100 93.3 100 100 N.A. 26.6 100 N.A. 26.6 N.A. N.A. 40 N.A. 33.3 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 37 0 10 10 10 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % F
% Gly: 55 46 0 10 0 0 19 0 0 10 0 10 0 0 0 % G
% His: 0 0 0 0 10 0 0 19 10 0 0 10 0 10 0 % H
% Ile: 0 10 0 0 0 0 0 10 0 10 0 0 0 0 0 % I
% Lys: 10 0 19 10 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 10 10 0 19 10 0 0 55 0 64 10 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 19 10 0 46 0 55 19 10 37 10 19 64 64 10 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % R
% Ser: 0 0 28 28 64 10 55 55 0 55 0 0 10 55 28 % S
% Thr: 0 10 10 0 0 10 0 10 0 0 0 10 0 10 37 % T
% Val: 10 0 0 0 0 0 0 0 0 10 10 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 10 0 0 0 0 0 0 0 10 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _