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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INO80E All Species: 18.18
Human Site: S143 Identified Species: 40
UniProt: Q8NBZ0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBZ0 NP_775889.1 244 26478 S143 S R Y P P F P S D Y L A L Q L
Chimpanzee Pan troglodytes XP_001147129 244 26500 S143 P R Y P P F P S D Y L A L Q L
Rhesus Macaque Macaca mulatta XP_001107210 244 26440 S143 P R Y P P F P S D Y L A L Q L
Dog Lupus familis XP_547064 244 26306 S143 P P Y P P F P S D Y L A L Q L
Cat Felis silvestris
Mouse Mus musculus NP_705808 205 21414 L131 R P R L P R K L K M S V G P P
Rat Rattus norvegicus Q6AYH2 244 26339 S143 P P Y P P F P S D Y L A L Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521309 217 23076 K141 K R P R L P R K L K M P V G P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_991199 231 25428 E143 E Y L A P S A E R V K K E R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_724986 291 31580 I188 A N H G I P A I A A K K Q L T
Honey Bee Apis mellifera XP_393482 236 27020 N156 T P I V Q S S N N I V P M S L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793894 280 31387 S148 L P H P A L L S P T V G M G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 99.1 96.7 N.A. 75.8 94.2 N.A. 78.6 N.A. N.A. 47.9 N.A. 25.7 35.2 N.A. 34.2
Protein Similarity: 100 99.1 99.1 96.7 N.A. 77.4 95.4 N.A. 81.9 N.A. N.A. 60.6 N.A. 38.4 49.1 N.A. 47.1
P-Site Identity: 100 93.3 93.3 86.6 N.A. 6.6 86.6 N.A. 6.6 N.A. N.A. 6.6 N.A. 0 6.6 N.A. 20
P-Site Similarity: 100 93.3 93.3 86.6 N.A. 6.6 86.6 N.A. 20 N.A. N.A. 13.3 N.A. 13.3 40 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 10 0 19 0 10 10 0 46 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 46 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 46 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 10 10 19 0 % G
% His: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 10 0 0 10 0 10 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 10 10 10 10 19 19 0 0 10 % K
% Leu: 10 0 10 10 10 10 10 10 10 0 46 0 46 10 64 % L
% Met: 0 0 0 0 0 0 0 0 0 10 10 0 19 0 0 % M
% Asn: 0 10 0 0 0 0 0 10 10 0 0 0 0 0 0 % N
% Pro: 37 46 10 55 64 19 46 0 10 0 0 19 0 10 19 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 10 46 0 % Q
% Arg: 10 37 10 10 0 10 10 0 10 0 0 0 0 10 0 % R
% Ser: 10 0 0 0 0 19 10 55 0 0 10 0 0 10 0 % S
% Thr: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % T
% Val: 0 0 0 10 0 0 0 0 0 10 19 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 46 0 0 0 0 0 0 46 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _