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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INO80E All Species: 20.3
Human Site: Y145 Identified Species: 44.67
UniProt: Q8NBZ0 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBZ0 NP_775889.1 244 26478 Y145 Y P P F P S D Y L A L Q L P E
Chimpanzee Pan troglodytes XP_001147129 244 26500 Y145 Y P P F P S D Y L A L Q L P E
Rhesus Macaque Macaca mulatta XP_001107210 244 26440 Y145 Y P P F P S D Y L A L Q L P E
Dog Lupus familis XP_547064 244 26306 Y145 Y P P F P S D Y L A L Q L P E
Cat Felis silvestris
Mouse Mus musculus NP_705808 205 21414 M133 R L P R K L K M S V G P P D C
Rat Rattus norvegicus Q6AYH2 244 26339 Y145 Y P P F P S D Y L A L Q L P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521309 217 23076 K143 P R L P R K L K M P V G P P E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_991199 231 25428 V145 L A P S A E R V K K E R K T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_724986 291 31580 A190 H G I P A I A A K K Q L T A T
Honey Bee Apis mellifera XP_393482 236 27020 I158 I V Q S S N N I V P M S L M S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793894 280 31387 T150 H P A L L S P T V G M G L P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 99.1 96.7 N.A. 75.8 94.2 N.A. 78.6 N.A. N.A. 47.9 N.A. 25.7 35.2 N.A. 34.2
Protein Similarity: 100 99.1 99.1 96.7 N.A. 77.4 95.4 N.A. 81.9 N.A. N.A. 60.6 N.A. 38.4 49.1 N.A. 47.1
P-Site Identity: 100 100 100 100 N.A. 6.6 100 N.A. 13.3 N.A. N.A. 6.6 N.A. 0 6.6 N.A. 26.6
P-Site Similarity: 100 100 100 100 N.A. 6.6 100 N.A. 26.6 N.A. N.A. 20 N.A. 6.6 33.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 19 0 10 10 0 46 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 0 46 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 55 % E
% Phe: 0 0 0 46 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 10 10 19 0 0 0 % G
% His: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 10 0 0 10 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 10 10 10 19 19 0 0 10 0 10 % K
% Leu: 10 10 10 10 10 10 10 0 46 0 46 10 64 0 10 % L
% Met: 0 0 0 0 0 0 0 10 10 0 19 0 0 10 0 % M
% Asn: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % N
% Pro: 10 55 64 19 46 0 10 0 0 19 0 10 19 64 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 10 46 0 0 0 % Q
% Arg: 10 10 0 10 10 0 10 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 0 19 10 55 0 0 10 0 0 10 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 10 10 10 % T
% Val: 0 10 0 0 0 0 0 10 19 10 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 46 0 0 0 0 0 0 46 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _