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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF149
All Species:
16.36
Human Site:
S334
Identified Species:
36
UniProt:
Q8NC42
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NC42
NP_775918.1
400
43165
S334
Q
E
M
P
A
P
E
S
P
P
G
R
D
P
A
Chimpanzee
Pan troglodytes
XP_515662
400
43217
S334
Q
E
M
P
A
P
E
S
P
P
G
R
D
P
A
Rhesus Macaque
Macaca mulatta
XP_001106945
400
42977
S334
Q
D
M
P
A
P
E
S
P
S
G
R
D
L
A
Dog
Lupus familis
XP_538454
383
42541
S282
Q
E
T
P
A
P
E
S
T
P
G
S
I
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3U2C5
394
42520
P328
D
T
Q
E
L
P
T
P
E
A
A
P
G
R
V
Rat
Rattus norvegicus
Q6Y290
419
46430
E329
D
N
V
A
F
D
M
E
R
L
T
R
T
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512667
679
72737
S596
Q
E
V
A
V
P
E
S
N
P
S
T
V
S
V
Chicken
Gallus gallus
Q90972
381
42801
S306
S
Q
E
E
N
E
V
S
E
N
T
P
L
L
R
Frog
Xenopus laevis
Q6NRX0
397
43453
S329
L
D
I
H
V
P
D
S
I
A
G
S
S
L
S
Zebra Danio
Brachydanio rerio
Q566M8
419
46332
E332
N
E
L
P
L
D
Y
E
L
A
V
G
G
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q06003
461
52604
D368
S
I
L
E
Y
Q
P
D
P
P
Q
G
L
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96
57.5
N.A.
77
39.3
N.A.
42.7
22.2
59.5
40.3
N.A.
31.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
97.5
63.5
N.A.
83.5
55.6
N.A.
47.8
39.7
72.7
58.4
N.A.
44.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
66.6
N.A.
6.6
13.3
N.A.
40
6.6
20
20
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
66.6
N.A.
6.6
20
N.A.
46.6
13.3
46.6
26.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
37
0
0
0
0
28
10
0
0
10
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
19
0
0
0
19
10
10
0
0
0
0
28
0
0
% D
% Glu:
0
46
10
28
0
10
46
19
19
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
46
19
19
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
10
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
19
0
19
0
0
0
10
10
0
0
19
37
10
% L
% Met:
0
0
28
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
10
0
0
0
10
10
0
0
0
0
0
% N
% Pro:
0
0
0
46
0
64
10
10
37
46
0
19
0
19
0
% P
% Gln:
46
10
10
0
0
10
0
0
0
0
10
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
37
0
10
10
% R
% Ser:
19
0
0
0
0
0
0
64
0
10
10
19
10
10
10
% S
% Thr:
0
10
10
0
0
0
10
0
10
0
19
10
10
0
0
% T
% Val:
0
0
19
0
19
0
10
0
0
0
10
0
10
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _