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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD6
All Species:
16.36
Human Site:
S125
Identified Species:
40
UniProt:
Q8NC69
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NC69
NP_001121686.1
237
27610
S125
E
E
V
V
E
L
S
S
T
R
K
L
S
K
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096089
228
26522
T117
E
V
V
E
L
S
S
T
R
K
L
S
K
Y
S
Dog
Lupus familis
XP_851103
260
29610
S140
I
Y
S
L
S
S
S
S
M
E
V
F
N
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNL5
237
27606
S125
E
E
V
V
E
L
S
S
T
R
K
L
S
K
Y
Rat
Rattus norvegicus
Q8R4G8
257
29416
V145
R
P
C
E
C
L
V
V
R
V
A
P
D
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505992
237
27536
S125
E
E
V
V
E
L
S
S
T
R
K
L
S
K
Y
Chicken
Gallus gallus
Q5ZJP7
289
33209
A178
I
E
I
A
K
L
R
A
V
Q
R
K
A
R
F
Frog
Xenopus laevis
Q6DCX3
255
29156
V144
F
Q
P
C
D
C
L
V
V
R
V
T
P
D
L
Zebra Danio
Brachydanio rerio
Q6DG99
237
27614
S125
E
Q
V
V
E
L
S
S
T
R
K
L
S
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179882
139
16035
M28
L
T
R
F
P
D
T
M
L
E
S
M
F
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.1
36.9
N.A.
99.1
28
N.A.
98.7
24.9
29
90.3
N.A.
N.A.
N.A.
N.A.
32
Protein Similarity:
100
N.A.
96.1
51.9
N.A.
100
45.5
N.A.
99.5
39
46.6
94.9
N.A.
N.A.
N.A.
N.A.
43.4
P-Site Identity:
100
N.A.
20
13.3
N.A.
100
6.6
N.A.
100
13.3
6.6
93.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
33.3
26.6
N.A.
100
6.6
N.A.
100
66.6
20
100
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
10
0
0
10
0
10
10
0
% A
% Cys:
0
0
10
10
10
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
10
0
0
0
0
0
0
10
10
0
% D
% Glu:
50
40
0
20
40
0
0
0
0
20
0
0
0
0
0
% E
% Phe:
10
0
0
10
0
0
0
0
0
0
0
10
10
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
20
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
10
40
10
10
40
0
% K
% Leu:
10
0
0
10
10
60
10
0
10
0
10
40
0
10
10
% L
% Met:
0
0
0
0
0
0
0
10
10
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% N
% Pro:
0
10
10
0
10
0
0
0
0
0
0
10
10
0
0
% P
% Gln:
0
20
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
10
0
10
0
0
0
10
0
20
50
10
0
0
10
0
% R
% Ser:
0
0
10
0
10
20
60
50
0
0
10
10
40
10
10
% S
% Thr:
0
10
0
0
0
0
10
10
40
0
0
10
0
0
0
% T
% Val:
0
10
50
40
0
0
10
20
20
10
20
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
40
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _