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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD6
All Species:
13.64
Human Site:
T116
Identified Species:
33.33
UniProt:
Q8NC69
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NC69
NP_001121686.1
237
27610
T116
K
P
L
Y
P
M
D
T
F
E
E
V
V
E
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096089
228
26522
F108
P
L
Y
P
M
D
T
F
E
E
V
V
E
L
S
Dog
Lupus familis
XP_851103
260
29610
P131
H
F
T
V
R
E
A
P
Q
I
Y
S
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNL5
237
27606
T116
R
P
L
Y
P
M
D
T
F
E
E
V
V
E
L
Rat
Rattus norvegicus
Q8R4G8
257
29416
F136
Q
D
R
E
T
S
R
F
S
R
P
C
E
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505992
237
27536
T116
K
P
L
Y
P
V
D
T
F
E
E
V
V
E
L
Chicken
Gallus gallus
Q5ZJP7
289
33209
R169
Y
Y
K
D
H
L
E
R
I
I
E
I
A
K
L
Frog
Xenopus laevis
Q6DCX3
255
29156
K135
K
Q
D
K
E
H
R
K
H
F
Q
P
C
D
C
Zebra Danio
Brachydanio rerio
Q6DG99
237
27614
T116
K
P
L
Y
P
L
D
T
F
E
Q
V
V
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179882
139
16035
A19
T
I
Y
T
T
S
R
A
T
L
T
R
F
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.1
36.9
N.A.
99.1
28
N.A.
98.7
24.9
29
90.3
N.A.
N.A.
N.A.
N.A.
32
Protein Similarity:
100
N.A.
96.1
51.9
N.A.
100
45.5
N.A.
99.5
39
46.6
94.9
N.A.
N.A.
N.A.
N.A.
43.4
P-Site Identity:
100
N.A.
13.3
0
N.A.
93.3
6.6
N.A.
93.3
13.3
6.6
86.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
13.3
6.6
N.A.
100
13.3
N.A.
100
40
20
100
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
10
10
10
% C
% Asp:
0
10
10
10
0
10
40
0
0
0
0
0
0
10
10
% D
% Glu:
0
0
0
10
10
10
10
0
10
50
40
0
20
40
0
% E
% Phe:
0
10
0
0
0
0
0
20
40
10
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
10
20
0
10
0
0
0
% I
% Lys:
40
0
10
10
0
0
0
10
0
0
0
0
0
10
0
% K
% Leu:
0
10
40
0
0
20
0
0
0
10
0
0
10
10
60
% L
% Met:
0
0
0
0
10
20
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
40
0
10
40
0
0
10
0
0
10
10
0
10
0
% P
% Gln:
10
10
0
0
0
0
0
0
10
0
20
0
0
0
0
% Q
% Arg:
10
0
10
0
10
0
30
10
0
10
0
10
0
0
0
% R
% Ser:
0
0
0
0
0
20
0
0
10
0
0
10
0
10
20
% S
% Thr:
10
0
10
10
20
0
10
40
10
0
10
0
0
0
0
% T
% Val:
0
0
0
10
0
10
0
0
0
0
10
50
40
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
20
40
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _