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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD6
All Species:
13.64
Human Site:
T221
Identified Species:
33.33
UniProt:
Q8NC69
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NC69
NP_001121686.1
237
27610
T221
S
E
R
A
N
E
N
T
V
E
H
N
W
T
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096089
228
26522
V213
E
R
A
N
E
N
T
V
E
H
N
W
T
F
C
Dog
Lupus familis
XP_851103
260
29610
F236
K
I
A
L
S
D
G
F
C
I
D
S
S
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNL5
237
27606
T221
S
E
R
A
N
E
N
T
V
E
H
N
W
T
F
Rat
Rattus norvegicus
Q8R4G8
257
29416
R241
V
L
R
R
E
L
R
R
T
P
R
V
P
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505992
237
27536
T221
S
E
R
A
N
E
N
T
V
E
H
N
W
T
F
Chicken
Gallus gallus
Q5ZJP7
289
33209
H274
C
D
K
H
L
I
N
H
Y
Y
C
K
R
P
I
Frog
Xenopus laevis
Q6DCX3
255
29156
R240
Y
V
L
C
R
E
D
R
R
M
Q
P
N
T
M
Zebra Danio
Brachydanio rerio
Q6DG99
237
27614
T221
S
E
R
A
N
E
N
T
V
E
H
H
W
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179882
139
16035
I124
T
Q
D
G
K
W
R
I
F
G
S
S
E
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.1
36.9
N.A.
99.1
28
N.A.
98.7
24.9
29
90.3
N.A.
N.A.
N.A.
N.A.
32
Protein Similarity:
100
N.A.
96.1
51.9
N.A.
100
45.5
N.A.
99.5
39
46.6
94.9
N.A.
N.A.
N.A.
N.A.
43.4
P-Site Identity:
100
N.A.
0
0
N.A.
100
6.6
N.A.
100
6.6
13.3
93.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
6.6
20
N.A.
100
13.3
N.A.
100
20
20
100
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
40
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
10
0
0
10
0
0
0
0
10
0
10
0
0
0
10
% C
% Asp:
0
10
10
0
0
10
10
0
0
0
10
0
0
0
0
% D
% Glu:
10
40
0
0
20
50
0
0
10
40
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
10
0
0
0
0
10
50
% F
% Gly:
0
0
0
10
0
0
10
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
10
0
10
40
10
0
10
0
% H
% Ile:
0
10
0
0
0
10
0
10
0
10
0
0
0
0
10
% I
% Lys:
10
0
10
0
10
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
10
10
10
10
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% M
% Asn:
0
0
0
10
40
10
50
0
0
0
10
30
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
10
10
10
10
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
10
50
10
10
0
20
20
10
0
10
0
10
0
0
% R
% Ser:
40
0
0
0
10
0
0
0
0
0
10
20
10
10
0
% S
% Thr:
10
0
0
0
0
0
10
40
10
0
0
0
10
60
0
% T
% Val:
10
10
0
0
0
0
0
10
40
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
10
40
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _