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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCTD6 All Species: 15.76
Human Site: Y184 Identified Species: 38.52
UniProt: Q8NC69 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NC69 NP_001121686.1 237 27610 Y184 F T F G P C D Y H Q E V S L R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001096089 228 26522 H176 T F G P C D Y H Q E V S L R V
Dog Lupus familis XP_851103 260 29610 E199 V E G L P E E E Y T K Q N L K
Cat Felis silvestris
Mouse Mus musculus Q8BNL5 237 27606 Y184 F T F G P C D Y H Q E V S L R
Rat Rattus norvegicus Q8R4G8 257 29416 V204 G Y C H L N S V Q V L E R L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505992 237 27536 Y184 F T F G P C D Y H Q E V S L R
Chicken Gallus gallus Q5ZJP7 289 33209 A237 V S F G P W E A V A D V Y D L
Frog Xenopus laevis Q6DCX3 255 29156 S203 N G Y C R L N S V Q V L E R L
Zebra Danio Brachydanio rerio Q6DG99 237 27614 Y184 F T F G P C D Y H Q E V S L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001179882 139 16035 Y87 L A Q E A D Y Y Q I K E L I D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.1 36.9 N.A. 99.1 28 N.A. 98.7 24.9 29 90.3 N.A. N.A. N.A. N.A. 32
Protein Similarity: 100 N.A. 96.1 51.9 N.A. 100 45.5 N.A. 99.5 39 46.6 94.9 N.A. N.A. N.A. N.A. 43.4
P-Site Identity: 100 N.A. 0 13.3 N.A. 100 6.6 N.A. 100 26.6 6.6 100 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 N.A. 13.3 46.6 N.A. 100 13.3 N.A. 100 46.6 26.6 100 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 0 0 10 0 10 0 0 0 0 0 % A
% Cys: 0 0 10 10 10 40 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 20 40 0 0 0 10 0 0 10 10 % D
% Glu: 0 10 0 10 0 10 20 10 0 10 40 20 10 0 0 % E
% Phe: 40 10 50 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 20 50 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 10 0 0 0 10 40 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 10 % K
% Leu: 10 0 0 10 10 10 0 0 0 0 10 10 20 60 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 10 10 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 10 60 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 30 50 0 10 0 0 10 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 0 10 20 40 % R
% Ser: 0 10 0 0 0 0 10 10 0 0 0 10 40 0 0 % S
% Thr: 10 40 0 0 0 0 0 0 0 10 0 0 0 0 0 % T
% Val: 20 0 0 0 0 0 0 10 20 10 20 50 0 0 10 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 0 0 0 20 50 10 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _