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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCTD6 All Species: 14.55
Human Site: Y197 Identified Species: 35.56
UniProt: Q8NC69 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NC69 NP_001121686.1 237 27610 Y197 L R V H L M E Y I T K Q G F T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001096089 228 26522 I189 R V H L M E Y I T K Q G F T I
Dog Lupus familis XP_851103 260 29610 P212 L K R L W V V P A N K Q I N S
Cat Felis silvestris
Mouse Mus musculus Q8BNL5 237 27606 Y197 L R V H L M E Y I T K Q G F T
Rat Rattus norvegicus Q8R4G8 257 29416 I217 L Q Q R G F E I V G S C G G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505992 237 27536 Y197 L R V H L M E Y I T K Q G F T
Chicken Gallus gallus Q5ZJP7 289 33209 T250 D L L H C I V T D L S D R G I
Frog Xenopus laevis Q6DCX3 255 29156 H216 R L F Q K G F H V A A S C G G
Zebra Danio Brachydanio rerio Q6DG99 237 27614 Y197 L R V H L M D Y I T K Q G F T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001179882 139 16035 K100 I D A V T Q A K E R A K E R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.1 36.9 N.A. 99.1 28 N.A. 98.7 24.9 29 90.3 N.A. N.A. N.A. N.A. 32
Protein Similarity: 100 N.A. 96.1 51.9 N.A. 100 45.5 N.A. 99.5 39 46.6 94.9 N.A. N.A. N.A. N.A. 43.4
P-Site Identity: 100 N.A. 0 20 N.A. 100 20 N.A. 100 6.6 0 93.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 N.A. 13.3 40 N.A. 100 33.3 N.A. 100 20 13.3 100 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 10 0 10 10 20 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 10 10 0 0 % C
% Asp: 10 10 0 0 0 0 10 0 10 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 10 40 0 10 0 0 0 10 0 10 % E
% Phe: 0 0 10 0 0 10 10 0 0 0 0 0 10 40 0 % F
% Gly: 0 0 0 0 10 10 0 0 0 10 0 10 50 30 20 % G
% His: 0 0 10 50 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 10 0 20 40 0 0 0 10 0 20 % I
% Lys: 0 10 0 0 10 0 0 10 0 10 50 10 0 0 0 % K
% Leu: 60 20 10 20 40 0 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 10 40 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 10 10 10 0 10 0 0 0 0 10 50 0 0 0 % Q
% Arg: 20 40 10 10 0 0 0 0 0 10 0 0 10 10 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 20 10 0 0 10 % S
% Thr: 0 0 0 0 10 0 0 10 10 40 0 0 0 10 40 % T
% Val: 0 10 40 10 0 10 20 0 20 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 40 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _