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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC37A3 All Species: 28.18
Human Site: S375 Identified Species: 51.67
UniProt: Q8NCC5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NCC5 NP_115671.1 494 54486 S375 V G S L I G Y S R S P N D K S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001107487 533 58234 S414 V G S L V G Y S R S P N D K A
Dog Lupus familis XP_539884 534 58913 S375 I G S L V G Y S R S P N D K S
Cat Felis silvestris
Mouse Mus musculus Q3TIT8 494 54534 S375 V W S L V G Y S R S P N N K S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508161 521 57005 S381 I G A L V G Y S R S P N D K S
Chicken Gallus gallus Q5F3N0 501 54893 S382 V G S L F G Y S R S P N S K P
Frog Xenopus laevis Q640L2 503 55582 S384 V G A L F G Y S H S P N D K V
Zebra Danio Brachydanio rerio Q7SY29 494 54021 N373 A P M L F L Y N K I G Q N G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001076702 502 56063 A382 G F F I G G P A N M I S S S I
Sea Urchin Strong. purpuratus XP_794537 476 52108 S362 M G S L Y G Y S V A P A N N W
Poplar Tree Populus trichocarpa XP_002324576 506 54265 V385 P A L V L Y R V Y G S V S M L
Maize Zea mays NP_001130713 495 52082 A360 P S L F L F H A Y G S T S K A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_178954 493 53038 V375 P A L I M Y R V Y G S V S M F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 88.3 85.3 N.A. 88.6 N.A. N.A. 76.9 78.6 70.7 35.2 N.A. N.A. N.A. 46.6 40.6
Protein Similarity: 100 N.A. 90 89.5 N.A. 93.9 N.A. N.A. 83.1 87.6 82.9 53.2 N.A. N.A. N.A. 62.5 59.9
P-Site Identity: 100 N.A. 86.6 86.6 N.A. 80 N.A. N.A. 80 80 73.3 13.3 N.A. N.A. N.A. 6.6 46.6
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 N.A. N.A. 100 80 80 33.3 N.A. N.A. N.A. 26.6 66.6
Percent
Protein Identity: 35.9 34.1 N.A. 34.6 N.A. N.A.
Protein Similarity: 56.5 54.3 N.A. 53.4 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 33.3 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 16 0 0 0 0 16 0 8 0 8 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 39 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 8 8 24 8 0 0 0 0 0 0 0 0 8 % F
% Gly: 8 54 0 0 8 70 0 0 0 24 8 0 0 8 0 % G
% His: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % H
% Ile: 16 0 0 16 8 0 0 0 0 8 8 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 0 0 0 62 0 % K
% Leu: 0 0 24 70 16 8 0 0 0 0 0 0 0 0 16 % L
% Met: 8 0 8 0 8 0 0 0 0 8 0 0 0 16 0 % M
% Asn: 0 0 0 0 0 0 0 8 8 0 0 54 24 8 0 % N
% Pro: 24 8 0 0 0 0 8 0 0 0 62 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 0 0 0 0 0 16 0 47 0 0 0 0 0 0 % R
% Ser: 0 8 47 0 0 0 0 62 0 54 24 8 39 8 31 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % T
% Val: 39 0 0 8 31 0 0 16 8 0 0 16 0 0 8 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 8 16 70 0 24 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _