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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HJURP
All Species:
9.09
Human Site:
S412
Identified Species:
40
UniProt:
Q8NCD3
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCD3
NP_060880.3
748
83539
S412
R
T
L
K
W
L
I
S
P
V
K
I
V
S
R
Chimpanzee
Pan troglodytes
XP_516170
744
82929
S412
R
T
L
Q
W
L
I
S
P
V
K
I
V
S
R
Rhesus Macaque
Macaca mulatta
XP_001110520
858
95361
S535
R
T
L
K
W
L
I
S
P
V
K
I
V
S
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q6PG16
667
74180
G347
L
K
S
V
S
L
E
G
S
K
R
Q
V
H
K
Rat
Rattus norvegicus
XP_237403
672
74816
K352
S
V
P
L
E
G
S
K
L
Q
V
H
K
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006255
582
66243
R262
K
Y
K
R
G
H
A
R
R
P
K
L
S
I
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
74.4
N.A.
N.A.
41.7
41.7
N.A.
N.A.
21.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.9
79
N.A.
N.A.
55.6
54.9
N.A.
N.A.
37.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
N.A.
N.A.
13.3
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
26.6
0
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
17
0
17
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
17
17
0
17
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
17
0
0
0
0
0
17
0
17
0
% H
% Ile:
0
0
0
0
0
0
50
0
0
0
0
50
0
17
0
% I
% Lys:
17
17
17
34
0
0
0
17
0
17
67
0
17
0
17
% K
% Leu:
17
0
50
17
0
67
0
0
17
0
0
17
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
17
0
0
0
0
0
50
17
0
0
0
0
0
% P
% Gln:
0
0
0
17
0
0
0
0
0
17
0
17
0
0
0
% Q
% Arg:
50
0
0
17
0
0
0
17
17
0
17
0
0
0
50
% R
% Ser:
17
0
17
0
17
0
17
50
17
0
0
0
17
50
17
% S
% Thr:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
17
% T
% Val:
0
17
0
17
0
0
0
0
0
50
17
0
67
0
0
% V
% Trp:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _