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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HJURP All Species: 9.09
Human Site: T239 Identified Species: 40
UniProt: Q8NCD3 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NCD3 NP_060880.3 748 83539 T239 D S L S L Q E T S S S S F L S
Chimpanzee Pan troglodytes XP_516170 744 82929 T239 D S L S L Q E T S S S S F L S
Rhesus Macaque Macaca mulatta XP_001110520 858 95361 T362 D S L S L Q E T S S S S F L S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q6PG16 667 74180 I181 A S G C Q D A I S A K S S G G
Rat Rattus norvegicus XP_237403 672 74816 F186 D G I P A K S F G G P E G S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006255 582 66243 D96 S V R R R F E D I H F Q N L D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 74.4 N.A. N.A. 41.7 41.7 N.A. N.A. 21.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.9 79 N.A. N.A. 55.6 54.9 N.A. N.A. 37.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 N.A. N.A. 20 6.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 26.6 26.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 17 0 17 0 0 17 0 0 0 0 17 % A
% Cys: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 67 0 0 0 0 17 0 17 0 0 0 0 0 0 17 % D
% Glu: 0 0 0 0 0 0 67 0 0 0 0 17 0 0 0 % E
% Phe: 0 0 0 0 0 17 0 17 0 0 17 0 50 0 0 % F
% Gly: 0 17 17 0 0 0 0 0 17 17 0 0 17 17 17 % G
% His: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % H
% Ile: 0 0 17 0 0 0 0 17 17 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 17 0 0 0 0 17 0 0 0 0 % K
% Leu: 0 0 50 0 50 0 0 0 0 0 0 0 0 67 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % N
% Pro: 0 0 0 17 0 0 0 0 0 0 17 0 0 0 0 % P
% Gln: 0 0 0 0 17 50 0 0 0 0 0 17 0 0 0 % Q
% Arg: 0 0 17 17 17 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 17 67 0 50 0 0 17 0 67 50 50 67 17 17 50 % S
% Thr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % T
% Val: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _