KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPRYD3
All Species:
4.55
Human Site:
T75
Identified Species:
14.29
UniProt:
Q8NCJ5
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCJ5
NP_116229.1
442
49694
T75
Y
V
A
S
R
P
L
T
K
D
S
N
Y
F
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028449
442
49678
T75
Y
V
A
S
R
P
L
T
K
D
S
N
Y
F
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085291
397
45063
V55
S
G
E
V
G
C
Y
V
A
P
R
P
L
S
K
Zebra Danio
Brachydanio rerio
NP_001099164
416
46824
E68
S
K
G
N
C
Y
F
E
V
T
I
M
D
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793412
501
55941
E115
I
A
L
V
D
L
T
E
E
E
N
F
F
E
V
Poplar Tree
Populus trichocarpa
XP_002325977
468
51945
K90
A
D
K
P
V
P
D
K
R
L
V
Y
Y
F
E
Maize
Zea mays
NP_001141511
466
52234
R95
A
D
R
P
A
P
T
R
R
A
V
Y
Y
F
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_973963
467
52331
K96
A
N
K
P
A
P
I
K
C
L
T
Y
Y
F
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
99.5
N.A.
N.A.
N.A.
N.A.
76
72.4
N.A.
N.A.
N.A.
N.A.
35.3
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
99.7
N.A.
N.A.
N.A.
N.A.
81.6
82.5
N.A.
N.A.
N.A.
N.A.
52.3
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
20.3
20.3
N.A.
22.2
N.A.
N.A.
Protein Similarity:
35
38.6
N.A.
39.4
N.A.
N.A.
P-Site Identity:
26.6
26.6
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
33.3
33.3
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
13
25
0
25
0
0
0
13
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
13
13
0
0
13
0
0
0
0
0
0
% C
% Asp:
0
25
0
0
13
0
13
0
0
25
0
0
13
0
0
% D
% Glu:
0
0
13
0
0
0
0
25
13
13
0
0
0
13
63
% E
% Phe:
0
0
0
0
0
0
13
0
0
0
0
13
13
63
0
% F
% Gly:
0
13
13
0
13
0
0
0
0
0
0
0
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
0
13
0
0
0
13
0
0
0
0
% I
% Lys:
0
13
25
0
0
0
0
25
25
0
0
0
0
0
13
% K
% Leu:
0
0
13
0
0
13
25
0
0
25
0
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% M
% Asn:
0
13
0
13
0
0
0
0
0
0
13
25
0
0
0
% N
% Pro:
0
0
0
38
0
63
0
0
0
13
0
13
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
13
0
25
0
0
13
25
0
13
0
0
0
0
% R
% Ser:
25
0
0
25
0
0
0
0
0
0
25
0
0
13
0
% S
% Thr:
0
0
0
0
0
0
25
25
0
13
13
0
0
13
0
% T
% Val:
0
25
0
25
13
0
0
13
13
0
25
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
25
0
0
0
0
13
13
0
0
0
0
38
63
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _