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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPRYD3
All Species:
7.88
Human Site:
Y335
Identified Species:
24.76
UniProt:
Q8NCJ5
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCJ5
NP_116229.1
442
49694
Y335
G
I
M
F
P
R
D
Y
I
L
D
S
E
G
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028449
442
49678
Y335
G
I
M
F
P
R
D
Y
I
L
D
S
E
G
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085291
397
45063
I311
P
R
C
Y
K
G
D
I
M
G
C
G
I
M
F
Zebra Danio
Brachydanio rerio
NP_001099164
416
46824
L324
M
F
P
R
D
Y
A
L
D
Y
E
D
E
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793412
501
55941
Y383
G
I
M
F
P
R
D
Y
Q
T
D
S
D
D
G
Poplar Tree
Populus trichocarpa
XP_002325977
468
51945
F349
F
L
L
H
S
Q
K
F
I
E
L
V
R
V
G
Maize
Zea mays
NP_001141511
466
52234
F361
G
R
A
N
L
A
S
F
L
T
H
E
A
F
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_973963
467
52331
E361
G
V
N
Y
G
R
L
E
L
A
K
F
V
G
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
99.5
N.A.
N.A.
N.A.
N.A.
76
72.4
N.A.
N.A.
N.A.
N.A.
35.3
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
99.7
N.A.
N.A.
N.A.
N.A.
81.6
82.5
N.A.
N.A.
N.A.
N.A.
52.3
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
20.3
20.3
N.A.
22.2
N.A.
N.A.
Protein Similarity:
35
38.6
N.A.
39.4
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
20
N.A.
N.A.
P-Site Similarity:
33.3
26.6
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
13
13
0
0
13
0
0
13
0
0
% A
% Cys:
0
0
13
0
0
0
0
0
0
0
13
0
0
0
0
% C
% Asp:
0
0
0
0
13
0
50
0
13
0
38
13
13
13
25
% D
% Glu:
0
0
0
0
0
0
0
13
0
13
13
13
38
0
25
% E
% Phe:
13
13
0
38
0
0
0
25
0
0
0
13
0
13
13
% F
% Gly:
63
0
0
0
13
13
0
0
0
13
0
13
0
38
25
% G
% His:
0
0
0
13
0
0
0
0
0
0
13
0
0
0
0
% H
% Ile:
0
38
0
0
0
0
0
13
38
0
0
0
13
13
0
% I
% Lys:
0
0
0
0
13
0
13
0
0
0
13
0
0
0
0
% K
% Leu:
0
13
13
0
13
0
13
13
25
25
13
0
0
0
13
% L
% Met:
13
0
38
0
0
0
0
0
13
0
0
0
0
13
0
% M
% Asn:
0
0
13
13
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
0
13
0
38
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
13
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
25
0
13
0
50
0
0
0
0
0
0
13
0
0
% R
% Ser:
0
0
0
0
13
0
13
0
0
0
0
38
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% T
% Val:
0
13
0
0
0
0
0
0
0
0
0
13
13
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
25
0
13
0
38
0
13
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _