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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APCDD1L All Species: 10.91
Human Site: S374 Identified Species: 30
UniProt: Q8NCL9 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NCL9 NP_699191.1 501 55635 S374 T T A M L N F S E P S S C G G
Chimpanzee Pan troglodytes XP_001134735 501 55673 S374 T T A M L N F S E P S S C G G
Rhesus Macaque Macaca mulatta XP_001118446 537 61156 F408 T A S L L N V F N G N E C G A
Dog Lupus familis XP_854723 541 60002 S417 T T A M L N F S E P S S C G G
Cat Felis silvestris
Mouse Mus musculus Q3U128 514 58619 F385 T A S L L N V F S G N E C G A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511045 479 54172 Q365 A R V T P M D Q V T V A M L N
Chicken Gallus gallus
Frog Xenopus laevis NP_001087578 515 58924 F384 T A S L L N V F N G D E C G A
Zebra Danio Brachydanio rerio XP_001341412 512 58247 T385 L L R E L N S T Q N G R C G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190332 481 54498 G358 N V G C G R R G A W K V G R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 44.6 75.5 N.A. 46.1 N.A. N.A. 60.8 N.A. 45.8 49.7 N.A. N.A. N.A. N.A. 35.1
Protein Similarity: 100 99.5 58.6 79.4 N.A. 60.5 N.A. N.A. 73 N.A. 62.1 62.8 N.A. N.A. N.A. N.A. 48.9
P-Site Identity: 100 100 33.3 100 N.A. 33.3 N.A. N.A. 0 N.A. 33.3 26.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 53.3 100 N.A. 53.3 N.A. N.A. 6.6 N.A. 46.6 40 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 34 34 0 0 0 0 0 12 0 0 12 0 0 34 % A
% Cys: 0 0 0 12 0 0 0 0 0 0 0 0 78 0 0 % C
% Asp: 0 0 0 0 0 0 12 0 0 0 12 0 0 0 0 % D
% Glu: 0 0 0 12 0 0 0 0 34 0 0 34 0 0 0 % E
% Phe: 0 0 0 0 0 0 34 34 0 0 0 0 0 0 0 % F
% Gly: 0 0 12 0 12 0 0 12 0 34 12 0 12 78 34 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % K
% Leu: 12 12 0 34 78 0 0 0 0 0 0 0 0 12 0 % L
% Met: 0 0 0 34 0 12 0 0 0 0 0 0 12 0 0 % M
% Asn: 12 0 0 0 0 78 0 0 23 12 23 0 0 0 12 % N
% Pro: 0 0 0 0 12 0 0 0 0 34 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 12 12 0 0 0 0 0 12 % Q
% Arg: 0 12 12 0 0 12 12 0 0 0 0 12 0 12 0 % R
% Ser: 0 0 34 0 0 0 12 34 12 0 34 34 0 0 0 % S
% Thr: 67 34 0 12 0 0 0 12 0 12 0 0 0 0 12 % T
% Val: 0 12 12 0 0 0 34 0 12 0 12 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _