KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNH5
All Species:
40
Human Site:
S421
Identified Species:
88
UniProt:
Q8NCM2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCM2
NP_647479.2
988
111907
S421
S
K
D
S
L
Y
V
S
S
L
Y
F
T
M
T
Chimpanzee
Pan troglodytes
XP_522873
1252
140079
S685
S
K
D
S
L
Y
V
S
S
L
Y
F
T
M
T
Rhesus Macaque
Macaca mulatta
XP_001100052
988
111890
S421
S
K
D
S
L
Y
V
S
S
L
Y
F
T
M
T
Dog
Lupus familis
XP_547846
988
111822
S421
S
K
D
S
L
Y
V
S
S
L
Y
F
T
M
T
Cat
Felis silvestris
Mouse
Mus musculus
Q920E3
988
111763
S421
S
K
D
S
L
Y
V
S
S
L
Y
F
T
M
T
Rat
Rattus norvegicus
Q9EPI9
988
111811
S421
S
K
D
S
L
Y
V
S
S
L
Y
F
T
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509563
961
108482
S425
S
K
D
S
V
Y
I
S
S
L
Y
F
T
M
T
Chicken
Gallus gallus
Q9PT84
526
59775
P33
Y
R
T
I
S
Q
I
P
Q
F
T
L
N
F
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664253
1005
113333
T423
G
K
D
S
L
Y
I
T
S
L
Y
F
T
M
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02280
1174
126352
T442
S
R
K
S
M
Y
V
T
A
L
Y
F
T
M
T
Honey Bee
Apis mellifera
XP_625212
1139
127116
T450
S
R
R
T
M
Y
V
T
A
L
Y
F
T
M
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.6
99.6
98.9
N.A.
97.8
98.1
N.A.
74.6
23.2
N.A.
78.1
N.A.
47.3
47.9
N.A.
N.A.
Protein Similarity:
100
78.7
99.9
99.2
N.A.
98.5
98.9
N.A.
85.2
35.6
N.A.
85.7
N.A.
61.7
64.3
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
0
N.A.
80
N.A.
66.6
60
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
13.3
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
73
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
91
0
10
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
28
0
0
0
0
0
0
0
0
% I
% Lys:
0
73
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
64
0
0
0
0
91
0
10
0
0
0
% L
% Met:
0
0
0
0
19
0
0
0
0
0
0
0
0
91
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
28
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
82
0
0
82
10
0
0
64
73
0
0
0
0
0
0
% S
% Thr:
0
0
10
10
0
0
0
28
0
0
10
0
91
0
91
% T
% Val:
0
0
0
0
10
0
73
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
91
0
0
0
0
91
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _