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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DYNC2H1 All Species: 23.03
Human Site: S471 Identified Species: 50.67
UniProt: Q8NCM8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NCM8 NP_001073932 4307 492594 S471 R G I P G D A S G P L S G K N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536596 4306 491933 S471 R G V P G E A S G P L S G K N
Cat Felis silvestris
Mouse Mus musculus Q45VK7 4306 492321 S471 R G I P G D P S G P L S G K N
Rat Rattus norvegicus Q9JJ79 4306 492200 S471 R G I P G D A S G P L S G K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509757 4391 500194 S562 H G A P G E L S G P L S G R N
Chicken Gallus gallus XP_417173 4301 491979 S469 H G V P G D V S G P L S G K N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P37276 4639 530166 S641 D L P P V A G S I I W A R Q I
Honey Bee Apis mellifera XP_395108 4023 452032 E445 R L M T L I R E A R A L S S Q
Nematode Worm Caenorhab. elegans Q19542 4171 473799 R450 A A R I V W I R Q Q T S Q M E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36022 4092 471329 S456 S L A E T I K S I S P S T Y H
Red Bread Mold Neurospora crassa P45443 4367 495560 H658 Q Y G H S E A H A M A Q L H D
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.5 N.A. 93.3 93 N.A. 85.8 79.7 N.A. N.A. N.A. 26.4 30.3 40.7 N.A.
Protein Similarity: 100 N.A. N.A. 96.5 N.A. 97.1 97 N.A. 91.8 89.4 N.A. N.A. N.A. 47.8 52.5 61.2 N.A.
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 93.3 100 N.A. 66.6 80 N.A. N.A. N.A. 13.3 6.6 6.6 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 93.3 100 N.A. 80 86.6 N.A. N.A. N.A. 26.6 13.3 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.8 27.6
Protein Similarity: N.A. N.A. N.A. N.A. 44.3 48.2
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 19 0 0 10 37 0 19 0 19 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 37 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 10 0 28 0 10 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 55 10 0 55 0 10 0 55 0 0 0 55 0 0 % G
% His: 19 0 0 10 0 0 0 10 0 0 0 0 0 10 10 % H
% Ile: 0 0 28 10 0 19 10 0 19 10 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 0 46 0 % K
% Leu: 0 28 0 0 10 0 10 0 0 0 55 10 10 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 10 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55 % N
% Pro: 0 0 10 64 0 0 10 0 0 55 10 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 10 10 0 10 10 10 10 % Q
% Arg: 46 0 10 0 0 0 10 10 0 10 0 0 10 10 0 % R
% Ser: 10 0 0 0 10 0 0 73 0 10 0 73 10 10 0 % S
% Thr: 0 0 0 10 10 0 0 0 0 0 10 0 10 0 0 % T
% Val: 0 0 19 0 19 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _