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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DYNC2H1 All Species: 24.24
Human Site: S826 Identified Species: 53.33
UniProt: Q8NCM8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NCM8 NP_001073932 4307 492594 S826 A G D E S I F S I M I D R N A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536596 4306 491933 S826 A G E E S I F S V M I D R N A
Cat Felis silvestris
Mouse Mus musculus Q45VK7 4306 492321 S826 A G D E S I F S V M I D R N A
Rat Rattus norvegicus Q9JJ79 4306 492200 S826 A G D E S I F S V M I D R N A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509757 4391 500194 T917 A G D E C I F T V M I E R N A
Chicken Gallus gallus XP_417173 4301 491979 T824 T E E E S I F T V M T E R N A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P37276 4639 530166 S989 A W Q A I V T S Q V R L Q S T
Honey Bee Apis mellifera XP_395108 4023 452032 E753 V G R L R G S E V K I W C I N
Nematode Worm Caenorhab. elegans Q19542 4171 473799 A788 E N S T K F Y A Q M I E R S M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36022 4092 471329 S767 W E S L Q E E S S E M S C S V
Red Bread Mold Neurospora crassa P45443 4367 495560 E982 A F E D E D V E R P S E R K R
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.5 N.A. 93.3 93 N.A. 85.8 79.7 N.A. N.A. N.A. 26.4 30.3 40.7 N.A.
Protein Similarity: 100 N.A. N.A. 96.5 N.A. 97.1 97 N.A. 91.8 89.4 N.A. N.A. N.A. 47.8 52.5 61.2 N.A.
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 93.3 93.3 N.A. 73.3 53.3 N.A. N.A. N.A. 13.3 13.3 20 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 93.3 80 N.A. N.A. N.A. 40 20 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.8 27.6
Protein Similarity: N.A. N.A. N.A. N.A. 44.3 48.2
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 20 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 64 0 0 10 0 0 0 10 0 0 0 0 0 0 55 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 19 0 0 % C
% Asp: 0 0 37 10 0 10 0 0 0 0 0 37 0 0 0 % D
% Glu: 10 19 28 55 10 10 10 19 0 10 0 37 0 0 0 % E
% Phe: 0 10 0 0 0 10 55 0 0 0 0 0 0 0 0 % F
% Gly: 0 55 0 0 0 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 55 0 0 10 0 64 0 0 10 0 % I
% Lys: 0 0 0 0 10 0 0 0 0 10 0 0 0 10 0 % K
% Leu: 0 0 0 19 0 0 0 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 64 10 0 0 0 10 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 55 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 10 0 10 0 0 0 19 0 0 0 10 0 0 % Q
% Arg: 0 0 10 0 10 0 0 0 10 0 10 0 73 0 10 % R
% Ser: 0 0 19 0 46 0 10 55 10 0 10 10 0 28 0 % S
% Thr: 10 0 0 10 0 0 10 19 0 0 10 0 0 0 10 % T
% Val: 10 0 0 0 0 10 10 0 55 10 0 0 0 0 10 % V
% Trp: 10 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _