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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DYNC2H1 All Species: 15.45
Human Site: Y1952 Identified Species: 34
UniProt: Q8NCM8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NCM8 NP_001073932 4307 492594 Y1952 Q V F E E A N Y E I I P N Q I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536596 4306 491933 Y1952 Q V F E E A N Y E I I P N Q I
Cat Felis silvestris
Mouse Mus musculus Q45VK7 4306 492321 Y1952 Q V F E E A N Y E V I P N Q M
Rat Rattus norvegicus Q9JJ79 4306 492200 Y1952 Q V F E E A N Y E V I P N Q M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509757 4391 500194 F2043 Q V F E D A N F E I I P T Q I
Chicken Gallus gallus XP_417173 4301 491979 L1949 E A F E E A R L E I I N T Q V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P37276 4639 530166 A2187 G E G D E Q G A A W M E K V L
Honey Bee Apis mellifera XP_395108 4023 452032 Q1790 L F E L C T E Q E L G K E M A
Nematode Worm Caenorhab. elegans Q19542 4171 473799 I1894 V A A Q E M G I K L G D K Q M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36022 4092 471329 S1859 R L D E K V L S A V S A N I Q
Red Bread Mold Neurospora crassa P45443 4367 495560 E2202 A S L E K L Q E A I R R L A A
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.5 N.A. 93.3 93 N.A. 85.8 79.7 N.A. N.A. N.A. 26.4 30.3 40.7 N.A.
Protein Similarity: 100 N.A. N.A. 96.5 N.A. 97.1 97 N.A. 91.8 89.4 N.A. N.A. N.A. 47.8 52.5 61.2 N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 86.6 86.6 N.A. 80 53.3 N.A. N.A. N.A. 6.6 6.6 13.3 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 93.3 66.6 N.A. N.A. N.A. 26.6 13.3 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.8 27.6
Protein Similarity: N.A. N.A. N.A. N.A. 44.3 48.2
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 40 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 19 10 0 0 55 0 10 28 0 0 10 0 10 19 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 10 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 10 10 10 73 64 0 10 10 64 0 0 10 10 0 0 % E
% Phe: 0 10 55 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 10 0 10 0 0 0 19 0 0 0 19 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 46 55 0 0 10 28 % I
% Lys: 0 0 0 0 19 0 0 0 10 0 0 10 19 0 0 % K
% Leu: 10 10 10 10 0 10 10 10 0 19 0 0 10 0 10 % L
% Met: 0 0 0 0 0 10 0 0 0 0 10 0 0 10 28 % M
% Asn: 0 0 0 0 0 0 46 0 0 0 0 10 46 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 46 0 0 0 % P
% Gln: 46 0 0 10 0 10 10 10 0 0 0 0 0 64 10 % Q
% Arg: 10 0 0 0 0 0 10 0 0 0 10 10 0 0 0 % R
% Ser: 0 10 0 0 0 0 0 10 0 0 10 0 0 0 0 % S
% Thr: 0 0 0 0 0 10 0 0 0 0 0 0 19 0 0 % T
% Val: 10 46 0 0 0 10 0 0 0 28 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 37 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _