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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYNC2H1
All Species:
21.21
Human Site:
Y2241
Identified Species:
46.67
UniProt:
Q8NCM8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCM8
NP_001073932
4307
492594
Y2241
T
R
G
R
L
A
T
Y
V
L
K
K
P
E
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536596
4306
491933
Y2241
S
R
R
R
L
A
S
Y
V
L
K
K
P
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q45VK7
4306
492321
Y2241
D
R
G
Q
L
A
S
Y
M
L
K
K
P
E
S
Rat
Rattus norvegicus
Q9JJ79
4306
492200
Y2241
D
R
G
Q
L
A
S
Y
V
L
K
K
P
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509757
4391
500194
Y2332
N
T
G
R
L
A
S
Y
K
L
K
K
P
E
N
Chicken
Gallus gallus
XP_417173
4301
491979
Y2238
D
S
G
Q
L
M
L
Y
R
L
K
K
P
E
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P37276
4639
530166
E2472
P
C
S
A
D
Q
L
E
H
Y
I
P
K
A
L
Honey Bee
Apis mellifera
XP_395108
4023
452032
L2066
Y
N
Q
N
T
D
R
L
E
T
V
G
D
A
D
Nematode Worm
Caenorhab. elegans
Q19542
4171
473799
Y2176
R
I
D
G
I
M
S
Y
T
D
D
V
S
Q
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36022
4092
471329
D2139
S
I
L
R
R
V
N
D
D
I
T
G
T
F
K
Red Bread Mold
Neurospora crassa
P45443
4367
495560
Y2480
A
V
R
D
I
I
E
Y
N
S
A
H
V
D
F
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.5
N.A.
93.3
93
N.A.
85.8
79.7
N.A.
N.A.
N.A.
26.4
30.3
40.7
N.A.
Protein Similarity:
100
N.A.
N.A.
96.5
N.A.
97.1
97
N.A.
91.8
89.4
N.A.
N.A.
N.A.
47.8
52.5
61.2
N.A.
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
66.6
73.3
N.A.
66.6
53.3
N.A.
N.A.
N.A.
0
6.6
6.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
86.6
86.6
N.A.
80
66.6
N.A.
N.A.
N.A.
0
6.6
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.8
27.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.3
48.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
46
0
0
0
0
10
0
0
19
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
28
0
10
10
10
10
0
10
10
10
10
0
10
10
19
% D
% Glu:
0
0
0
0
0
0
10
10
10
0
0
0
0
55
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% F
% Gly:
0
0
46
10
0
0
0
0
0
0
0
19
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% H
% Ile:
0
19
0
0
19
10
0
0
0
10
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
55
55
10
0
10
% K
% Leu:
0
0
10
0
55
0
19
10
0
55
0
0
0
0
10
% L
% Met:
0
0
0
0
0
19
0
0
10
0
0
0
0
0
0
% M
% Asn:
10
10
0
10
0
0
10
0
10
0
0
0
0
0
37
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
10
55
0
0
% P
% Gln:
0
0
10
28
0
10
0
0
0
0
0
0
0
10
0
% Q
% Arg:
10
37
19
37
10
0
10
0
10
0
0
0
0
0
0
% R
% Ser:
19
10
10
0
0
0
46
0
0
10
0
0
10
0
19
% S
% Thr:
10
10
0
0
10
0
10
0
10
10
10
0
10
0
0
% T
% Val:
0
10
0
0
0
10
0
0
28
0
10
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
73
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _